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Pharmaceutical Process Development Articles & Analysis
52 articles found
Among the various production systems available, Chinese Hamster Ovary (CHO) cells have emerged as a gold standard for monoclonal antibody production, and specialized services have been developed to streamline this process. The Significance of CHO Cells CHO cells are favored for their eukaryotic nature, which allows for proper post-translational modifications, ...
Introduction PEGylation, the process of attaching polyethylene glycol (PEG) chains to therapeutic molecules, has become a cornerstone in pharmaceutical development. ...
These crucial compounds undergo rigorous research, development, and manufacturing processes before being integrated into final pharmaceutical formulations. ...
Understanding the metabolic stability of potential drug candidates is paramount in the realm of pharmaceutical development. S9 metabolic stability assays provide critical insights into how a compound behaves within biological systems, especially concerning its metabolism, stability, and overall pharmacokinetics. ...
These films offer unique advantages in terms of dosage accuracy and controlled release, which are critical in pharmaceutical development. At the forefront of this innovation is CD Formulation, a company that caters to pharmaceutical research entities looking to develop advanced oral drug delivery systems. ...
In the realm of pharmaceutical research and development, ADME testing services play a pivotal role in evaluating the pharmacokinetics of drug candidates. ...
In the rapidly evolving field of pharmaceuticals, nanotechnology has emerged as a revolutionary force, transforming the landscape of drug delivery and formulation development. The integration of nanotechnology into pharmaceutical formulation offers unprecedented opportunities to enhance the efficacy, safety, and convenience of therapeutic interventions. This article explores the profound impact ...
In vitro permeability assay kits play a crucial role in the field of pharmaceutical development, particularly when evaluating the absorption characteristics of drugs. ...
In the rapidly evolving world of biotechnology, synthetic peptides have emerged as a pivotal component with wide-ranging applications in medical research, diagnostics, and therapeutic developments. These lab-created sequences of amino acids mimic naturally occurring peptides and are instrumental in advancing scientific discoveries and pharmaceutical innovations. ...
In the ever-evolving world of pharmaceutical development, the quest to innovate and improve the delivery of drug substances remains a top priority. ...
HCPs are purified together with the target product during the production process and cannot be removed. Risks of HCPs In general, HCP constitutes the major process-related impurity in the drug product in addition to the target protein. ...
Ongoing research and inventions in the field of oncology focus on the development of small molecule drug therapies for use in brain tumor resection. Small molecule drugs are being developed to target and effectively treat brain tumors to improve therapeutic outcomes. Small particles containing compounds that can enter cells and interact with specific targets to inhibit or modulate their ...
The intestinal flora is involved in many physiological and pathological processes in the host, including digestion and absorption of food, metabolism of certain nutrients and pharmaceutical compounds, development of host immunity, intestinal inflammatory states, and more. ...
Huateng Pharma, a leading Contract Development and Manufacturing Organization (CDMO), is proud to announce the launch of its latest product, Piroctone Olamine (CAS: 68890-66-4). This addition underscores Huateng Pharma’s commitment to providing high-quality pharmaceutical ingredients to meet the diverse needs of the global health and personal care industries. Piroctone Olamine is a highly ...
Pharmaceutical Stability Analysis Pharmaceutical stability analysis is a key aspect of pharmaceutical development and quality control. ...
Microspheres play a crucial role in the field of pharmaceuticals, biotechnology, and materials science due to their unique properties and applications. These spherical particles, ranging from a few micrometers to several millimeters in size, have a wide range of uses, including drug delivery systems, cell encapsulation, and as supports for various chemical reactions. Polymeric microspheres, ...
This scientifically recognized process leads to fewer gastrointestinal issues, including gas and bloating. ...
Patient-centric drug development is a divisive concept. Dismissed as a buzzword by some. Adopted extensively by others. ...
In the world of pharmaceuticals, developing safe and effective drugs is a complex and time-consuming process. ...
Carfilzomib, a proteasome inhibitor, is indicated for the treatment of patients with multiple myeloma. Multiple myeloma (multiple myeloma, MM) is a malignant tumor originating from the B cell lineage, characterized by the clonal proliferation of malignant plasma cells in the bone marrow microenvironment, causing fractures and bone marrow failure, and is the second most common blood system ...