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Physiological In Vivo System Articles & Analysis
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ENPP2 Catalytic Features (Structured Summary) Feature Description Functional Implication Phosphodiesterase Domain Hydrolyzes LPC to LPA Generates bioactive lipid signals Somatomedin B-like Domains Bind integrins/ECM Localizes enzyme activity to specific microenvironments Substrate Specificity Preference for LPC acyl chain length Determines LPA species and downstream receptor activation ...
Active Pharmaceutical Ingredients (APIs) form the foundation of modern pharmaceuticals, serving as the biologically active components responsible for the therapeutic effects of medications. These crucial compounds undergo rigorous research, development, and manufacturing processes before being integrated into final pharmaceutical formulations. The pharmaceutical landscape encompasses a diverse ...
The cardiopulmonary system is recognized as one of the most essential physiological systems in the human body, with the responsibility of efficiently distributing blood and oxygen to every organ. The cardiopulmonary system is closely linked to human health. Therefore, pulmonary function testing is crucial for both disease prevention and diagnosis.Since different diseases lead to distinct ...
Microbes are present almost everywhere. They play a vital role in cycling carbon, release important compounds, and may be associated with infectious diseases. Metagenomics is the culture-independent genomic research of microbial communities. Metagenomics presents a powerful tool to study prokaryotes and viruses in the environment via the analysis of their DNA obtained directly from environmental ...
Published by Vijay K Singh and Thomas M Seed on September 3, 2021, in Expert Opinion on Drug Discovery and deals with the necessity of animal models for modern drug research in the direction of animal strains, animal models, requirements, and pathways for developing new drugs. The use of experimental animal models in drug development aids in the understanding of disease and/or related conditions' ...