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Physiological State Articles & Analysis

9 articles found

Unveiling the Role of Nicotinamide Adenine Dinucleotide (NAD): A Key Player in Cellular Metabolism and Disease Research   

Unveiling the Role of Nicotinamide Adenine Dinucleotide (NAD): A Key Player in Cellular Metabolism and Disease Research  

Measuring the dynamic levels of NAD/NADH in biological systems can provide invaluable insights into the metabolic and physiological state of an organism. Why Is NAD/NADH Analysis Important? ...

ByCreative Proteomics


Understanding Anorexia Through the Study of Ground Squirrels During Hibernation

Understanding Anorexia Through the Study of Ground Squirrels During Hibernation

Anorexia, a condition characterized by a significant reduction in food intake despite negative energy balance, poses severe risks to health and quality of life. It manifests in various forms in humans, including anorexia nervosa and physiological anorexia. While psychological and social factors have been widely studied, the physiological causes remain less understood. For ground squirrels, ...

Byemka Technologies S.A.S


Application of Lipidomics in the Pharmaceutical Research

Application of Lipidomics in the Pharmaceutical Research

Lipidomics studies lipids in organisms at a systematic level, revealing their interactions and interactions with other biomolecules. Many abnormal physiological states are associated with disorders of lipid metabolism. Studying the changes of lipids in different states of the organism at the systemic level can help analyze the mechanisms of ...

ByCreative Proteomics


An In-depth Analysis of hERG (IKr, Kv11.1): Its Function, Role, and Importance

An In-depth Analysis of hERG (IKr, Kv11.1): Its Function, Role, and Importance

This article delves into the function, role, and importance of hERG in the heart's normal physiology and various disease states. The Structure, Function, and Role of hERG (IKr, Kv11.1) The hERG-encoded protein forms a voltage-gated K+ channel that contributes to the delayed rectifier current, IKr, in cardiac myocytes. ...

ByCreative Bioarray


Unsaturated Omega-3 and Omega-6 Fatty Acids

Unsaturated Omega-3 and Omega-6 Fatty Acids

An excessive omega-6:omega-3 ratio shifts the physiological state of tissues towards the pathogenesis of many diseases, such as blood clots, inflammation, etc. ...

ByCreative Proteomics


Enhancing Human Gut Tissue Models through Gene Editing

Enhancing Human Gut Tissue Models through Gene Editing

Once prepared, the genetically engineered, self-renewing stem cells can be frozen, providing an indefinite supply of cells with the causative or relevant mutation for that disease state. In essence, we see RepliGut® as a platform upon which gene editing of cells can serve as a unique resource to pharmaceutical companies and/or basic biologists interested in evaluating stem ...

ByAltis Biosystems


Evaluating Microbiome Therapies with Intestinal Cell Models

Evaluating Microbiome Therapies with Intestinal Cell Models

With that information in hand, it is possible to investigate the differences between normal physiology and disease states to determine what goes wrong with stem cells during disease processes and ultimately to evaluate how different treatments for disease can impact stem cells. ...

ByAltis Biosystems


Pilot Validation of a New Wireless Patch System as an Ambulatory, Noninvasive Tool That Measures Gut Myoelectrical Signals: Physiologic and Disease Correlations

Pilot Validation of a New Wireless Patch System as an Ambulatory, Noninvasive Tool That Measures Gut Myoelectrical Signals: Physiologic and Disease Correlations

Results: The inherent reproducibility of the WPS measurement technique itself and from the underlying gut activity, coupled with source validation and sensitivity to changes in gut activity in several physiologic and pathologic states, demonstrates its feasibility, safety, and performance in clinical settings. ...

ByG-Tech Medical


Assessment of correlation between physiological states of <italic>Escherichia coli</italic> cells and their susceptibility to chlorine using flow cytometry

Assessment of correlation between physiological states of <italic>Escherichia coli</italic> cells and their susceptibility to chlorine using flow cytometry

The physiological differences of individual cells of bacterial population may imply the existence of cell subpopulations with different sensitivity to chlorine, which may affect the efficiency of drinking water disinfection. The susceptibility of individual bacterial cells to chlorine was examined using flow cytometry. The inactivation of Escherichia coli cells by chlorine in the populations ...

ByIWA Publishing

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