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Pulmonary Arterial Articles & Analysis
5 articles found
Precision-Cut Lung Slices (PCLS) have emerged as a innovative ex vivo model that allows researchers to explore deep into lung physiology, disease mechanisms, and pharmacological responses. By offering a unique combination of biological complexity and controlled experimental conditions, PCLS serve as a critical bridge between the limitations of traditional in vitro cell cultures and the ...
Heart failure with preserved ejection fraction (HFpEF) has recently been recognized as the single greatest unmet need in cardiovascular medicine, overtaking heart failure with reduced ejection fraction (HFrEF) and becoming the most common form of heart failure, with a prevalence that is increasing by 1% annually.[1] Despite this, there remains no gold standard in diagnosing HFpEF. Diagnosing ...
Abstract Acute decompensated heart failure remains the most common cause of hospitalization in older adults, and studies of pharmacological therapies have yielded limited progress in improving outcomes for these patients. This has prompted the development of novel device–based interventions, classified mechanistically based on the way in which they intend to improve central hemodynamics, ...
Glycosaminoglycan (GAG) is a general term for the glycan part of proteoglycan macromolecules. Glycosaminoglycans are large linear polysaccharides composed of repeating disaccharide units, and their main configuration contains amino sugars and uronic acids (glucuronic acid and/or iduronic acid). Glycosaminoglycans can be divided into chondroitin sulfate, dermatan sulfate, keratan sulfate, ...
Abstract Cancer patients frequently develop tumor and treatment-related complications, leading to diminished quality of life, shortened survival, and overutilization of emergency department and hospital services. Outpatient oncology treatment has potential to leave cancer patients unmonitored for long periods while at risk of clinical deterioration which has been exaggerated during the COVID19 ...