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Skeletal Muscle Articles & Analysis

18 articles found

Understanding Skeletal Muscle Microvascular Endothelial Cells: A Crucial Component of Muscle Health

Understanding Skeletal Muscle Microvascular Endothelial Cells: A Crucial Component of Muscle Health

Skeletal muscle microvascular endothelial cells (SMECs) play an essential role in maintaining muscle function, metabolism, and overall health. These specialized cells line the blood vessels within skeletal muscles, forming a barrier that regulates the exchange of substances between the bloodstream and muscle tissue. Their significance extends beyond mere structural support; they actively ...

ByCreative Bioarray


DMS in Identifying Cancer-Relevant Phospholipids

DMS in Identifying Cancer-Relevant Phospholipids

An article on the identification of phospholipids relevant to cancer tissue using DMS has been published in the International Journal of Molecular Sciences! Identification of three cancer-relevant phospholipids, phosphatidylcholine (PC), phosphatidylinositol (PI), and phosphatidylethanolamine (PE) was studied. As a step forward from our previous study of lecithin, this time individual ...

ByOlfactomics


Regulation of Lipid Metabolism in the Intestinal Flora

Regulation of Lipid Metabolism in the Intestinal Flora

Trillions of microorganisms live in the gastrointestinal tract, far outnumbering the body's own cells. The intestinal flora is involved in many physiological and pathological processes in the host, including digestion and absorption of food, metabolism of certain nutrients and pharmaceutical compounds, development of host immunity, intestinal inflammatory states, and more. Dysbiosis of the ...

ByCreative Proteomics


The Science Behind Dietary Supplements: Exploring Efficacy and Safety of Popular Ingredients

The Science Behind Dietary Supplements: Exploring Efficacy and Safety of Popular Ingredients

Dietary supplements have become increasingly popular in recent years as individuals seek to optimize their health and well-being. When it comes to popular dietary supplement ingredients, several categories stand out, including vitamins, minerals, amino acids, enzymes, botanicals, and more. Each of these components plays a crucial role in supporting various physiological functions in the human ...

ByAlfa Chemistry


Significance of Diagnostic Enzyme Detection

Significance of Diagnostic Enzyme Detection

Serum enzyme tests have been used in clinical practice for a long time, such as increased amylase activity in serum and urine of patients with acute pancreatitis. In the 1930s, some scholars reported that the determination of serum lipase and alkaline phosphatase activities is helpful for the diagnosis of pancreatitis and bone diseases, respectively. After the 1950s, the application of serum ...

ByCreative Enzymes


Baroreflex Activation Therapy: A Novel Approach for HFrEF Patients

Baroreflex Activation Therapy: A Novel Approach for HFrEF Patients

During the webinar, you’ll learn about: Treatment options and unmet needs of HFrEF patients The physiologic rationale of baroreflex activation Barostim therapy overview and clinical evidence overview Appropriate patient selection and real-world experience Important Safety Information CAUTION: Federal law restricts this device to sale by or on the ...

ByCVRx


Solutions Built to Cure - Case study

Solutions Built to Cure - Case study

Whether you are a physiotherapist who is treating a patient or someone who would like to receive rehabilitation safely at home, BECURE is ready to help you. The Problem Physiotherapy (physical therapy) is used for the rehabilitation of neurological, orthopedic, pediatric, geriatric, and rheumatologic diseases; to diagnose muscle-skeletal system diseases; and to treat them. It is a holistic ...

ByBeCure


Everything You Want to Know About Lipoprotein Lipase

Everything You Want to Know About Lipoprotein Lipase

Lipoprotein lipase (LPL) is a glycoprotein synthesized and secreted by parenchymal cells such as adipocytes, cardiomyocytes, skeletal muscle cells, mammary cells, and macrophages, with a molecular weight of 60ku and containing 3-8% carbohydrates. The physiological function of LPL is to catalyze the breakdown of TG in the core of CM and VLDL into fatty acids and monoglycerides for tissue oxidative ...

ByCreative Enzymes


We put the O2 in WRKUT

We put the O2 in WRKUT

Over the course of time, humankind has been continuously searching for methods to remain young, preserve their health and become more and more efficient in all aspects of their existence. Especially nowadays, in the fast-paced world that we all live in, it is important to maintain a balanced lifestyle and to prioritize the health of our bodies and minds. But do you really have the time to ...

ByOXYHELP INDUSTRY


Huateng Pharma Supplies Canagliflozin Intermediates With Commercial Scale Production

Huateng Pharma Supplies Canagliflozin Intermediates With Commercial Scale Production

Canagliflozin is a medication used to treat type 2 diabetes. It is a third-line medication to be tried after metformin, a first-line medication for type 2 diabetes. It is used together with exercise and diet. It is not recommended in type 1 diabetes. Mechanism action of Canagliflozin Canagliflozin is a sodium-glucose cotransporter (SGLT2) inhibitor. Glucose filtered in the renal tubular lumen is ...

ByHunan Huateng Pharmaceutical Co. Ltd.


Vitamins: Types and Their Functions

Vitamins: Types and Their Functions

Vitamin A: Helps body growth and tissue repair, helps with eye health, fights bacteria to avoid infection, protects epithelial tissue health, and promotes bone and tooth development. Vitamin B1: Promotes the metabolism of carbohydrates, maintains a healthy nervous system, stabilizes appetite, stimulates growth and maintains good muscle condition. Vitamin B2: Promotes the metabolism of ...

ByCreative Proteomics


Exercise in the morning or in the evening has a completely distinct effect!   

Exercise in the morning or in the evening has a completely distinct effect!  

Life is all about working out. Moderate exercise not only strengthens the body, but also improves the metabolic state and slows the progression of diseases. However, different times of exercise may have different impacts, and it is an intriguing scientific question how to determine the best time to exercise. Although the influence of exercise on energy metabolism is well recognized, there is ...

ByCreative Biolabs


Unsaturated Omega-3 and Omega-6 Fatty Acids

Unsaturated Omega-3 and Omega-6 Fatty Acids

What are unsaturated fatty acids? Unsaturated fatty acids are a type of fatty acids that make up body fat and are indispensable to the human body. Unsaturated fatty acids are divided into monounsaturated fatty acids and polyunsaturated fatty acids, depending on the number of double bonds. In food fat, monounsaturated fatty acids include oleic acid and other fatty acids. Polyunsaturated fatty ...

ByCreative Proteomics


Application of Enzyme Detection in Clinical Diagnosis

Application of Enzyme Detection in Clinical Diagnosis

Serum enzyme tests have been used in clinical practice for a long time, such as increased amylase activity in serum and urine of patients with acute pancreatitis. In the 1930s, some scholars reported that the determination of serum lipase and alkaline phosphatase activities is helpful for the diagnosis of pancreatitis and bone diseases, respectively. After the 1950s, the application of serum ...

ByCreative Enzymes


The Importance of Lactate Testing in Sports and Performance Training

The Importance of Lactate Testing in Sports and Performance Training

In fine tuning performance in competitive sports, lactate testing makes the difference, so how can testing lactate thresholds sharpen performance? To get ahead in sports means dedication, training and a considered diet. Getting these factors right can mean the difference between winning and losing. In fine tuning achievement in competitive sports lactate testing makes the difference, so how can ...

ByAnalox Instruments Ltd


Mercury and selenium concentrations in skeletal muscle, liver and regions of the heart and kidney in bearded seals from Alaska

Mercury and selenium concentrations in skeletal muscle, liver and regions of the heart and kidney in bearded seals from Alaska

Mean concentrations of total mercury [THg] and selenium [TSe] (mass and molar based) were determined for five regions of the heart and two regions of the kidney of bearded seals (Erignathus barbatus) harvested in Alaska in 2010–2011. Mean [THg] and [TSe] of bearded seal liver and skeletal muscle tissues were used for intertissular comparison. Se:Hg molar ratios were used to investigate ...

ByJohn Wiley & Sons, Ltd.


Increased insulin action in skip heterozygous knockout mice

Increased insulin action in skip heterozygous knockout mice

Insulin controls glucose homeostasis and lipid metabolism, and insulin impairment plays a critical role in the pathogenesis of diabetes mellitus. Human skeletal muscle and kidney enriched inositol polyphosphate phosphatase (SKIP) is a member of the phosphatidylinositol 3,4,5-trisphosphate phosphatase family (T. Ijuin et al. J. Biol. Chem. 275:10870-10875, 2000; T. Ijuin and T. Takenawa, Mol. ...

ByAmerican Society for Microbiology (ASM)


Repression of prespliceosome complex formation at two distinct steps by fox-1/fox-2 proteins

Repression of prespliceosome complex formation at two distinct steps by fox-1/fox-2 proteins

Precise and robust regulation of alternative splicing provides cells with an essential means of gene expression control. However, the mechanisms that ensure the tight control of tissue-specific alternative splicing are not well understood. It has been demonstrated that robust regulation often results from the contributions of multiple factors to one particular splicing pathway. We report here a ...

ByAmerican Society for Microbiology (ASM)

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