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Stem Cell Transplantation Articles & Analysis
6 articles found
What is CAR T-cell therapy? Car-t cell therapy involves genetically engineering T cells isolated from patients or allogeneic donors to express chimeric antigen receptors (CAR) that specifically recognize and kill tumor cells. ...
And many people who receive intensive chemotherapy or stem cell transplants can experience side effects such as infection, hair loss and vomiting, as well as long-term complications. ...
The key to this patient's recovery was a blood stem cell transplant: The researchers first used chemotherapy drugs to kill the patient's own immune cells and then transplanted new cells that would not be infected by HIV. ...
Gene-modified cell therapies (GMCTs) represent the most effective therapeutic platform for many patients with advanced diseases including relapsed and refractory leukemia, non-Hodgkin lymphoma, and other blood cancers [1]. Specifically, chimeric antigen receptor T cell (CAR-T) therapies targeting CD19 have demonstrated remarkable responses and possibly cures in patients with advanced acute ...
Introduction The classical field of neuroscience entails biological or psychological investigation of the nervous system, including the brain, spinal cord and the systemic network of sensory nerve cells called neurons.1 Traditionally, this field comprised of purely biological studies but has since flourished into an interdisciplinary sphere addressing the developmental, ...
Abstract Natural killer (NK) cells hold promise for improving the therapeutic potential of allogeneic hematopoietic transplantation, but their effectiveness is limited by inhibitory HLA types. ...