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Therapy Medical Device Articles & Analysis
22 articles found
One of the biggest challenges clinical data management faces is the sheer amount of data that needs to be processed. With more and more patient data becoming available, it can be difficult for CDM systems to keep up. In addition, many CDM systems are not user-friendly or interactive, making it difficult for users to get the most out of them. What challenges do clinical data management systems ...
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Pulmonary fibrosis, particularly idiopathic pulmonary fibrosis (IPF), represents a significant challenge in healthcare due to its detrimental impact on lung function and limited treatment options. While WNT/β-catenin signaling plays a crucial role in lung development and maintenance of adult lung stem cells, its dysregulation has been associated with pulmonary fibrosis. However, recent ...
Therefore, medical device manufacturers consider four factors to reach a final medical device shelf life determination following FDA and ISO medical device shelf life standards. ...
In the search for innovative and effective ways to target cancer, we are faced with more than just a challenging problem; we are faced with our own cells as opponents. Cancer cells evolve to achieve an optimum of physical fitness, giving them an array of abilities that no cell should possess in a healthy organism. One way to find novel therapies against cancer therefore could imply finding a ...
Antibody-drug conjugate (ADC) is one of the fastest growing fields in tumor therapy, which consists of monoclonal antibody (Antibody), linker (Linker) and active drug (Payload). So far, there are only 15 drugs on the market in the world. However, with the development of some perfect antibody modification techniques, advanced site-specific coupling techniques and powerful small-molecule toxins, ...
Chitin is the second largest natural polymer after cellulose, and it exists widely in nature, such as shells of crustaceans such as shrimps, crabs, insects, and cell walls of fungi. Although chitin has good biocompatibility and biodegradability, its poor solubility limits its practicality in the field of biomedicine. The product of chitin deacetylation is chitosan. Chitosan is structurally ...
Abstract: A concern regarding osteochondral autograft transfer for chondral defects is donor-site morbidity of the knee, the most common source of the autograft. To avoid the drawbacks of osteochondral autograft transfer, a cylindrical osteoperiosteal graft harvested from the iliac crest covered by a same-sized cylinder of hyaluronic acidebased polymer scaffold pretreated with bone marrow ...
Challenges Faced in Studies of Device-Based Therapies for ADHF While the details of future studies will depend highly on device particulars, there are several common key strategic, clinical, regulatory, and reimbursement questions applicable to the devices reviewed in this paper. ...
Alucent Biomedical Inc. is rethinking peripheral artery disease (PAD) treatment with a novel natural scaffolding technology based on a light-activated drug therapy delivered via a balloon catheter. This first-of-its-kind drug-device therapy, known as Natural Vascular Scaffolding (AlucentNVS), is designed to provide a more natural and effective ...
Alzheimer's disease (AD) is a progressive, irreversible neurodegenerative disease clinically manifested by cognitive impairment, behavioral abnormalities, and social deficits. It is predicted that by 2050, the number of people 65 and older with dementia in the United States could reach 13.8 million. In China, more than 15.07 million elderly people aged 60 or over suffer from dementia, of which ...
The pelvic floor physical therapy system is a therapeutic method that uses physical therapy concepts to recondition the pelvic floor muscles in a systematic, effective, and safe manner. The treatment’s purpose is to increase the strength and function of the pelvic floor muscles, as well as to relieve discomfort, weakness, and inefficiency. A qualified physical therapist accesses the muscles ...
Vesper Medical will further expand Philips’ portfolio of diagnostic and therapeutic devices with an advanced venous stent portfolio for the treatment of deep venous disease. ...
What are AAVs? and what makes them good candidates for gene therapy? In two previous posts, we introduced gene therapy, a method for curing genetic diseases by providing healthy copies of defective genes, and Adeno-associated virus (AAV) capsids, the gene therapy delivery system Dyno focuses on. In those posts, we also discussed how natural variants of AAV did not evolve for the specialized ...
Abstract The ZAP-X® is a newly designed, self-contained, and first-of-its-kind self-shielded therapeutic radiationtherapy device dedicated to brain and head and neck stereotactic radiosurgery (SRS). By using an S-bandlinear accelerator (linac) and employing integrated minimal but sufficient shielding, the ZAP-X does nottypically require a radiation bunker. At the same time, the self-shielded ...
The US Food and Drug Administration (FDA) requires that all medical devices are identified with a unique device identifier (UDI), in both human and machine-readable forms. ...
On Friday, March 27, President Trump enacted the Defense Production Act to order General Motors (“GM”) to assist Ventec Life Systems with the mass production of a ventilator that incorporates multiple lifesaving therapies into one machine (Ventilator, Oxygen, Cough Assist, Suction, Nebulizer). AG Industries provides a critical component for this ...
At the beginning of Chinese New Year, Beijing Yaguo Technology Co., Ltd.'s innovative medical device "Respiratory Power" respiratory neuromuscular stimulator was officially launched. "Respiratory power" has been established in 2015 as a core innovative product of Yaguo, Through 4 years of continuously efforts, after research, demonstration, design, development, ...
The multicenter, nonrandomized, prospective study is assessing the system in patients with symptomatic heart failure and concomitant functional mitral regurgitation (FMR) who have stable symptoms on guideline-directed medical therapy. “Early safety and efficacy data on the transcatheter Accucinch system is impressive and suggests the ...
Interim study results from systolic heart failure patients treated with percutaneous therapy designed to improve left ventricular function presented at TCT 2019 Santa Clara, ...
Quast, Beurskens and colleagues remark that a completely extracardiac pacing system provides the potential for clinical advantages over existing device alternatives that require intravascular, endocardial, or epicardial contact, and that preliminary studies evaluating the feasibility of cardiac pacing with a lead in the anterior mediastinum, outside the pericardium and ...