Tumor Associated Cell Articles & Analysis
2 articles found
However, due to the loss of MHC molecules, tumor cells are usually resistant to αβ T cell attacks. In contrast, γδ T cells, expressing γδ TCR, are effector cells in the innate immune system, which function in an MHC-unrestricted manner, making them ideal mediators for cancer immunotherapy. ...
Endosomal escape means that mRNA needs to be released from the endosomal vesicles, and then combined with the host cell ribosome to be translated into antigen proteins, which are modified and secreted out of the cell to play a role. ...