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Ultrafiltration Articles & Analysis

9 articles found

Downstream Processing Development: Unlocking Efficiency and Innovation in Biopharmaceutical Manufacturing

Downstream Processing Development: Unlocking Efficiency and Innovation in Biopharmaceutical Manufacturing

Membrane technologies such as ultrafiltration, diafiltration, and viral filtration have also matured, offering faster and more scalable solutions. ...

ByCreative BioMart


CMC Regulatory Considerations for ADCs

CMC Regulatory Considerations for ADCs

Generally speaking, the process change of ADC payload-linker intermediate is controllable, because in the typical ADC production process, there are usually purification steps such as ultrafiltration/deep filtration (UF/DF) or chromatography to remove impurities after coupling reaction. ...

ByBOC Sciences


Biotin PEG

Biotin PEG

The more commonly used methods are: ultrafiltration with 0.1 M PBS buffer, or dialysis. Since there are many types of biotins and they are usually in the form of powder, a suitable solvent should be selected when dissolving. ...

ByBOC Sciences


What are Host Cell Proteins and Its Effect on Biopharmaceutical Development

What are Host Cell Proteins and Its Effect on Biopharmaceutical Development

The interaction between HCPs and therapeutic proteins is first removed by anionic surfactants, so that HCPs can be enriched using a molecular weight cut-off (MWCO) ultrafiltration step, and then identified by a "shotgun" quantitative proteomics technique and analysis of HCP in therapeutic protein drugs. ...

ByCreative Proteomics


Protecting IC systems with Metrohm Inline Ultrafiltration and Inline Dialysis

Protecting IC systems with Metrohm Inline Ultrafiltration and Inline Dialysis

A more efficient way to prepare samples for IC analysis is by using Metrohm Inline Sample Preparation (MISP) techniques to automate the process. Either Metrohm Inline Ultrafiltration (UF) or Inline Dialysis can be used to safeguard the IC system from harmful matrix components while simultaneously reducing manual labor and increasing sample ...

ByB&W Tek


Project - Horizon 2020 EIC

Project - Horizon 2020 EIC

This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No. ...

ByParagate Medical


Conceptual Considerations for Device-Based Therapy in Acute Decompensated Heart Failure

Conceptual Considerations for Device-Based Therapy in Acute Decompensated Heart Failure

In contrast to loop diuretics, which remove primarily hypotonic urine, cause large volume shifts, and lead to relative renal hypoperfusion, ultrafiltration slowly removes isotonic fluid. Additionally, ultrafiltration does not decrease sodium delivery to the macula densa and thus mechanistically avoids the neurohomornal activation and accompanying sodium and water ...

BySecond Heart Assist, Inc.


Sources, Functions and Therapeutic Applications of Bromelain

Sources, Functions and Therapeutic Applications of Bromelain

Stem Bromelain (SBM) As the name suggests, this type of bromelain is extracted from the stem of the pineapple plant by centrifugation, ultrafiltration or freeze-drying, and is widely available in the market. Because it is cheaper to extract and the pineapple stem is basically worthless. 2. ...

ByCreative Enzymes


Pediatric benefits fact sheet

Pediatric benefits fact sheet

Because children have more delicate immune systems than adults, water contaminants pose a more serious threat to the young. Drinking only the highest quality water is one way that parents can contribute to keeping their children healthy, even before they are born. Pregnant women need to be especially careful of the water they drink. Certain levels of some water contaminants such as lead, nitrate ...

ByKinetico Europe ApS - an Axel Johnson Company

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