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Vaccine Excipients Nucleic Acid Delivery Articles & Analysis
16 articles found
Virus-like particles (VLPs) have garnered significant attention in recent years for their potential applications in vaccine development, drug delivery, and as tools in various biotechnological fields. These nanoparticles mimic the structure of viruses but lack the viral genetic material that makes viruses infectious. This unique characteristic offers a versatile platform for various innovative ...
Gene delivery is a therapeutic strategy that’s revolutionizing biotechnology and pharmaceuticals. It involves the delivery of new genetic molecules into target cells to treat diseases. This technology has the implicit to revise the treatment of inherited genetic disorders, cancer and other intractable driseases. Scientists are using a variety of gene delivery strategies to insert new ...
Alfa Cytology has announced cancer diagnostic biomarker development services to enhance precision in oncology research. Alfa Cytology, a pioneering biotech firm comprising an interdisciplinary team of scientists, bioinformaticians, and oncologists, has recently introduced its cancer diagnostic biomarker development services to advance personalized cancer treatment strategies. Cancer diagnosis ...
Introduction Advancements in medical technology have led to innovative solutions for various healthcare challenges. One breakthrough is microneedle patch technology, holding immense promise in revolutionizing drug delivery. These patches consist of micron-sized needles that painlessly penetrate the skin's outermost layer, enabling the controlled release of medications or therapeutic agents. In ...
Glycerin, a versatile and widely used compound, finds its application in various industries, including pharmaceuticals. By understanding the multifaceted applications of glycerin in vaccine formulation, storage, and delivery, pharmaceutical manufacturers can optimize their vaccine production processes to ensure superior quality and effectiveness. Among the numerous components and additives ...
Each year malaria kills hundreds of thousands of people – mostly children – around the globe, and according to a report by the WHO, in 2021 nearly half of the world’s population was at risk of malaria. This included infants, children under 5 years of age, pregnant women, patients with HIV/AIDS, etc. Moreover, over the two peak years of the pandemic, COVID-related disruptions ...
Abera’s vaccine delivery platform works as a plug-and-play system where known or novel antigens can be engineered onto our delivery platform to create effective, multivalent vaccines that are cost-effective and fast to produce. We actively work together with academia and industry to enable the use of our vaccine delivery platform in design and development of new vaccines. Many of these ...
Liposomes are a novel drug delivery system (DDS). They are bimolecular vesicles that form spontaneously when phospholipids are dispersed in water. Liposomes vary in size, composition and charge and can be used as carriers for a wide range of drug molecules, such as chemotherapeutic agents, antimicrobial and antiviral drugs, antiparasitic drugs, genetic material, vaccines, therapeutic proteins, ...
Study will measure immune responses generated by M2SR and high dose vaccine separately and in combination in the highly vulnerable 65-85 years old population – Funded by the US Department of Defense, this study is expected to yield topline data in 2H 2022 – MADISON, Wis., June 22, 2022 /PRNewswire/ — FluGen, Inc., a clinical-stage vaccine company transforming vaccine ...
Jonathan “Jake” Kurtis was riding a night train from Nairobi to Mombasa when he first began to feel sick. Then a 20-year-old Brown junior, Kurtis had gone to the restaurant car for a curry and stayed up late drinking beer with some Americans he’d met. By the time he got back to his sleeper car, he had a vicious headache. “I thought God had visited upon me a righteous ...
RNA is a hydrophilic, negatively charged macromolecule, and its ability to autonomously transmembrane is limited. Therefore, how to efficiently deliver mRNA to the cytoplasm and play a corresponding role is one of the key issues that limit the application of RNA therapy. The wide range of applications of therapeutic mRNA requires efficient and safe delivery methods. An ideal delivery system ...
For research facilities, hospitals, clinics, doctor offices and other medical establishments, vaccine storage is absolutely critical to ensuring the accuracy and efficiency of vaccines administered. Although regulatory organizations carry out standard audits to examine vaccine storage procedures, it is important to conduct internal auditing. Especially in the times we are facing now with a global ...
There are several potential COVID-19 vaccines that may soon be available for widespread distribution. In particular, the United Kingdom has recently approved Pfizer’s vaccine, and the U.S. Food and Drug Administration is considering extending Emergency Use Authorization to the Pfizer and Moderna vaccines. That is certainly promising news, but storage, transportation, and delivery of these ...
Vaccine Storage and Handling Vaccines and other medical products are essential parts of a healthy society. They provide relief from diseases and suffering. They are designed to improve the quality of life for people. As with any other product, they are manufactured in facilities located near urban centers. When shipped elsewhere, transportation is provided by a cold chain process in place to ...
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All vaccines are sensitive to extreme heat and extreme cold and require both proper vaccine storage and management to avoid any loss of potency. Immunization is the most effective and economical public health measure against infectious diseases that cause morbidity or mortality. Immunization prevents two to three million deaths every year from diseases such as hepatitis, pertussis (whooping ...
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Chitosan binds to negatively charged tripolyphosphate (TPP) by an electrostatic interaction driven by its positively charged amino group. This interaction allows developing stable nanoparticles suitable as a carrier and controlled release system for drugs and vaccines. We study the effect of chitosan nanoparticles (CNp) on the uptake and antigen presentation of the model protein hen-egg white ...