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Vascular Abi System Articles & Analysis

8 articles found

ENPP2: Autotaxin as a Master Regulator of Lipid-Mediated Cellular Signaling

ENPP2: Autotaxin as a Master Regulator of Lipid-Mediated Cellular Signaling

Lipids are not merely structural components of cellular membranes—they also act as powerful signaling molecules that orchestrate key physiological processes. Among the enzymes regulating lipid signaling, ENPP2 (Ectonucleotide Pyrophosphatase/Phosphodiesterase 2), also known as autotaxin, plays a central role by converting lysophosphatidylcholine (LPC) into the bioactive lipid ...

ByCreative BioMart


Marker Bands in Medical Imaging and Interventional Procedures

Marker Bands in Medical Imaging and Interventional Procedures

Marker bands serve a critical function in medical imaging and interventional procedures, offering Marker bands are essential for precise visualization during medical treatments. Designed for visibility under fluoroscopic imaging, these radiopaque bands, made from materials like platinum-iridium alloy, gold, and tantalum, play a critical role in healthcare applications. They enhance accuracy in ...

ByEdgetech Industries LLC


Cerebral angiography: investigating the brain's "tree of life."

Cerebral angiography: investigating the brain's "tree of life."

The human brain has long been regarded as one of the most enigmatic subjects in both medicine and science, captivating interest since ancient times. Its intricate architecture and advanced functionalities continue to inspire awe. However, it is through the lens of contemporary medical technology that we can begin to uncover the secrets within the brain, revealing the intricate structures nestled ...

ByEdgetech Industries LLC


Matrix Metalloproteinases (MMPs) - Structure, Sources and Functions

Matrix Metalloproteinases (MMPs) - Structure, Sources and Functions

Structure of Matrix Metalloproteinase (MMP) Family In vertebrates, the MMP family consists of 28 members, at least 23 of which are expressed in human tissues, 14 of which are expressed in the vascular system. MMPs are usually classified into collagenases, gelatinases, stromelysins, matrilysins, membrane-type (MT)-MMPs, and other MMPs based on their substrates and the organization of their ...

ByCreative Proteomics


Three generations of ADC: Nearly a decade of development-PII   

Three generations of ADC: Nearly a decade of development-PII  

Kadcyla and second-generation non-cleavable linkers Alternative linker design methodologies are still under development. Immunogen discovered a very powerful ADC by an accidental discovery. The lysine residue of trastuzumab is linked to DM1 via a non-cleavable linker containing N-succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC), an ADC (T-DM1, Kadcyla) authorized by the FDA in ...

ByCreative Biolabs


Israeli artificial pancreas may one day cure diabetes

Israeli artificial pancreas may one day cure diabetes

The Engineered Micro Pancreas from Betalin Therapeutics is heading closer to clinical trials in humans. Ahead of International Diabetes Day, November 14, Israeli startup Betalin Therapeutics announced that it is beginning the application process for clinical trials of its revolutionary artificial pancreas. Betalin’s Engineered Micro Pancreas (EMP) aims to free patients suffering from the ...

ByBetalin Therapeutics Ltd.


How to Choose Antifreeze

How to Choose Antifreeze

Non-freezing liquid for cars is a product of mass use. It is not possible to do without it in the cold season, because this substance allows to keep car windshields clean, thereby providing good visibility to the driver and improving road safety. Today the market of automobile goods is quite diverse, so you can find antifreeze of both domestic and foreign production without any problem. We ...

ByGlobeCore - Biodiesel Division


Novel ‘3D’ Stent Improves Clinical Status in Femoropopliteal Disease Patients

Novel ‘3D’ Stent Improves Clinical Status in Femoropopliteal Disease Patients

PARIS, France—A "3D" helical stent that mimics the natural vascular curvature helps improve clinical symptoms and walking distance at 12 months in patients with femoropopliteal disease, according to results presented Tuesday, May 21 at EuroPCR 2013. For the Mimics study, researchers led by Stephan H. Duda, MD, of Jewish Hospital Berlin (Berlin, Germany), randomized 76 patients with ...

ByVeryan Medical Ltd.

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