Vasculitis Articles & Analysis
2 articles found
l Cystic fibrosis (CF): Neutrophilic inflammation in the CF lung is exacerbated by high ELANE levels, promoting mucus hypersecretion, airway remodeling, and bacterial persistence. l Rheumatoid arthritis and vasculitis: ELANE damages endothelial barriers and exposes autoantigens, further fueling immune activation. ...
At that point, an attempt was made to enroll her into the PROMISE I United States feasibility study, but she was excluded because of her vasculitis. This patient had no options except another BTK amputation. We reached out to LimFlow, Inc. and our hospital (University Hospitals Cleveland Medical Center) to consider a compassionate use of LimFlow to save this patient’s leg. ...