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Glycosylation site detection refers to identifying the location where glycosylation occurs in biomolecules. Glycosylation is a biochemical modification process that involves linking sugar molecules to other biomolecules (such as proteins, nucleic acids, or lipids), thereby affecting their structure and function. Glycosylation plays a critical role in organisms, but it may also be associated with ...
The antibody sequence can be used to create vaccines, develop new treatment strategies, and even analyze the functioning of the immune system. Below is the basic process of discovering new antibodies through sequencing.Prepare SamplesImmune cell samples, such as lymphocytes, are obtained from the patient or experimental animals. These cells are the sources of antibody generation, and their ...
Introduction to Genome-wide Association Studies A genome-wide association study is what the National Institutes of Health call "a study of common genetic variation across the whole human genome with the goal of finding genetic links to observable traits."Even though family linkage studies and studies with tens of thousands of gene-based SNPs measure genetic variation across the genome, the ...
Bioinformatics is a discipline developed on the basis of biology, mathematics and computer science. It effectively acquires and analyzes biological data such as nucleic acid sequences and protein structures, so as to conduct comprehensive and accurate biological analysis. Bioinformatics is an extremely important tool to study the microorganisms, which are widespread and highly varied. ...
Biomarkers are defined as measurable biological characteristics that are associated with normal or pathological conditions. They possess clinical relevance, including diagnostic, prognostic, and predictive values. RNA, not only an essential part of the central dogma, is certainly a relatively untapped resource for biomarker discovery of various diseases. Cumulating data shows that RNA ...