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Disease Detection Articles & Analysis
29 articles found
As the new year begins, many people prioritize their health by scheduling annual physicals and medical check-ups. While these routine exams ensure overall well-being, few realize the crucial role that fluoropolymers play in modern medical technology. From diagnostic tools to life-saving devices, fluoropolymer materials contribute significantly to patient safety, hygiene, and the accuracy of ...
Exosomes, small vesicles released by cells, play an increasingly prominent role in intercellular communication and disease modulation. These nano-sized particles contain a diverse array of molecular cargo, including proteins, lipids, RNA, and metabolites, which serve as biomarkers for a variety of physiological conditions. Exosome lipidomics and metabolomics are key fields that focus on profiling ...
Cytokines and growth factors are essential signaling molecules that play pivotal roles in immune regulation, inflammation, tissue repair, and numerous physiological and pathological processes. To comprehensively study these molecules, scientists often rely on high-throughput and sensitive technologies, among which Luminex Cytokine Panels have become a gold standard. This article delves into the ...
Acetylation detection of a specific protein is a method used to determine whether and where acetylation modifications have occurred on a protein. Acetylation is a common post-translational modification of proteins, typically occurring on lysine residues of proteins, and plays a crucial role in regulating protein function, cell signaling, gene expression, and disease onset. For instance, the ...
Histone SUMOylation is a post-translational modification that involves the covalent linking of the SUMO protein to the lysine residues of histones. This process requires the participation of a series of enzymes, including E1 activating enzyme, E2 conjugating enzyme and E3 ligase. SUMOylation plays a key role in gene expression regulation, DNA repair, RNA processing and nuclear transport in the ...
In the grand symphony of life, there are countless unsung heroes quietly orchestrating the countless chemical reactions that sustain our world. These remarkable biomolecules, known as enzymes, are the true MVPs (Most Valuable Proteins) that keep our planet thriving. Enzymes are nature's own specialized workforce, each one tailored to catalyze a specific reaction. Imagine a team of highly ...
Rare diseases, also known as orphan diseases, affect a small percentage of the population, making them particularly challenging to diagnose and treat. However, thanks to advancements in medical research and technology, significant progress has been made in the field of rare disease research, from developing accurate diagnostic tools to making effective small-molecule drugs. One of the biggest ...
Rare diseases are characterized by their low prevalence, affecting a small number of people across the world. These diseases often come with significant challenges, including accurate diagnosis, availability of effective treatments, and limited resources for research and development. However, recent advancements in diagnostics technology hold promise for speeding up the field of rare disease ...
Abstract Background: Preeclampsia is a major pregnancy complication that results in significant maternal and infant mortality, most of which occurs in low and middle-income countries. The accurate and timely diagnosis of preeclampsia is critical in management of affected pregnancies to reduce maternal and fetal/neonatal morbidity and mortality, yet difficulties remain in establishing the rigorous ...
Nano-flow cytometry is a revolutionary technology that has the potential to transform early disease detection and diagnosis. Nano-flow cytometers are able to detect and analyze individual nanoparticles, including extracellular vesicles and viruses, with high sensitivity and accuracy. This makes them ideal for detecting diseases at their earliest stages, when they are most treatable. How does ...
Luminex multiplex assays is a multi-functional, multi-indicator parallel analysis system that organically integrates color-coded beads, laser technology, applied fluidics, the latest high-speed digital signal processor and computer algorithms to create a high degree of specificity and sensitivity for multi-factor detection. It can be widely used in immunoassay, nucleic acid research, enzymatic ...
The diagnosis and treatment of rare diseases have long been a daunting challenge due to their complex and often undefined nature. However, with recent advancements in technology, specifically in the realm of genomics, whole genome sequencing (WGS) has emerged as a powerful tool that has revolutionized the diagnosis and management of rare diseases. This groundbreaking technique offers hope to ...
Enzymes, nature's molecular architects, have been at the heart of industrial processes for decades. Today, the dynamic field of Enzyme Engineering and Modification is driving these biocatalysts towards unprecedented capabilities, triggering a wave of transformative applications across diverse sectors. Decoding Enzyme Engineering Enzyme Engineering stands as a cornerstone of modern ...
Enzymes are protein molecules that catalyze chemical reactions in living organisms. They are involved in many metabolic processes and play a critical role in maintaining the health of the body. In recent years, enzymes have been widely used in disease diagnosis, providing a quick and accurate way to detect and monitor diseases. Enzymes for disease diagnosis can be divided into two categories: ...
Enzymes are biological catalysts that accelerate chemical reactions in living organisms. In recent years, enzymes have been increasingly utilized in medical diagnostics, leading to significant advancements in disease detection and management. Enzyme-based diagnostic tools have revolutionized the healthcare industry, offering numerous benefits such as increased accuracy, sensitivity, and speed. ...
While the world continues to endure loss and hardship due to the outbreak of COVID-19, caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), researchers are scrambling to provide test kits that are accurate, fast, sensitive, and widely available, especially as symptoms vary broadly and may not appear for days if at all. To this end, several diagnostic methods have been ...
Background Several pioneering studies have provided evidence for the introduction of universal pulse oximetry screening for critical congenital heart disease. I lowever, whether the benefits of screening reported in studies from high-income countries would translate with similar success to low-income countries is unknown. We assessed the feasibility and reliability of pulse oximetry plus clinical ...
When automated dark adaptometry was first commercialized, many of us had more questions than answers with regard to using this information for detecting AMD and monitoring disease progression. But with more than seven years of practical in-office experience performing dark adaptation testing on thousands of patients, the tables have turned. This technology offers a safety net for ...
Pediatric Short Bowel Syndrome (also called SBS or Short Gut Syndrome) generally develops shortly after birth due to an underlying gastrointestinal (GI) condition. The condition then can lead to intestinal surgery, in which part of the short bowel is removed. SBS is a devastating condition where patients struggle to absorb life-sustaining nutrients from their diet due to the surgical removal of ...
What is it? Posturography is a non-evasive technique that quantifies an individual’s balance behavior in upright stance. As mentioned in previous articles (What is Balance?), balance is achieved and maintained by a complex set of sensorimotor control systems, which includes the visual, somatosensory and vestibular systems. It is through their integration in real time by the central ...