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Liver Model Articles & Analysis

2 articles found

Improved 3D Liver Model Could Forever Change Drug Testing – Allevi Author

Improved 3D Liver Model Could Forever Change Drug Testing – Allevi Author

The liver plays an incredibly important role in the human body by metabolizing drugs and other compounds. Developing accurate in vitro liver models to study is a critical step in better understanding the biological dynamics of our bodies and removing our dependence on animal models. In their recent publication, Allevi authors Marie Cuvellier, Frédéric Ezan, Hugo Oliveira, Sophie ...

ByAllevi, Inc.


	 Utilization of a 3D bioprinted liver tissue model to evaluate the antifibrotic effects of an ALK5 inhibitor in a TGFß-induced model of hepatic fibrosis

Utilization of a 3D bioprinted liver tissue model to evaluate the antifibrotic effects of an ALK5 inhibitor in a TGFß-induced model of hepatic fibrosis

Publication Summary: Compound induced chronic liver injury can lead to initiation of profibrotic processes resulting in sustained production of growth factors and profibrotic cytokines where inflammation, tissue remodeling and repair pathways are activated simultaneously to counteract the injury. Evaluation of potential antifibrotic therapies are limited using conventional non-human animal ...

ByOrganovo Holdings Inc.

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