Metabolic Control Articles & Analysis
3 articles found
Sugar nucleotides are key molecules in the biosynthesis of glycans, which are carbohydrate chains found on the surface of cells or in the bloodstream. These molecules play a critical role in a wide range of biological processes, including cell signaling, protein folding, and immune responses. In this article, we will delve into the structure and synthesis of sugar nucleotides, and explore their ...
The filamentous fungus Aspergillus fumigatus is responsible for a lethal disease called invasive aspergillosis that affects immunocompromised patients. This disease, like other human fungal diseases, is generally treated by compounds targeting the primary fungal cell membrane sterol. Recently, glucan synthesis inhibitors were added to the limited antifungal arsenal and encouraged the search for ...
Corynebacterium glutamicum 2262 strain, when triggered for glutamate excretion, experiences a rapid decrease in growth rate and increase in glutamate efflux. In order to gain a better quantitative understanding of the factors controlling the metabolic transition, the fermentation dynamics was investigated for a temperature-sensitive strain cultivated in batch and glucose-limited continuous ...