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Endocrine System Articles & Analysis
14 articles found
Lipids, often simply thought of as fats, play a far more complex and vital role in our bodies than just energy storage. They are fundamental building blocks for cell membranes, crucial for nutrient absorption, and, significantly, the precursors to a powerful class of signaling molecules: steroid hormones. Understanding the deep connection between Lipid Metabolism and these hormones, along with ...
Removal of API’s, EC’s & EDC’s via Nyex Rosalox™ Technology We recently discussed the removal of active pharmaceutical ingredients (API’s) and emerging contaminants (EC’s) in the environment – see Removal of Active Pharmaceutical Ingredients from Water . Endocrine Disrupting Chemicals (EDCs) is another category of compounds whose presence in the ...
ByCoftec
Some substances can easily interact with the oxygen in the air when exposed to the air, causing chemical changes in the substance. This is the process of oxidation. Sun exposure, air pollution, radiation, etc. will cause the human skin to produce a large amount of superoxide free radicals, and its strong oxidizing ability will accelerate the speed of skin oxidation, and may even cause serious ...
In this article we examine the legal and political moves to regulate endocrine disruptors over the past 20 years and the most recent developments in this regard… There is growing concern in the EU and worldwide about the negative human health and environmental impacts possibly caused by endocrine disruptors. So, what are endocrine disruptors (ED)? They are chemicals that may interfere ...
The US Environmental Protection Agency has responsibility for assessing endocrine activity of more than 10 000 chemicals, a task that cannot reasonably be achieved solely through use of available mammalian and nonmammalian in vivo screening assays. Hence, it has been proposed that chemicals be prioritized for in vivo testing using data from in vitro high‐throughput assays for specific ...
Endocrine disrupting compounds (EDCs) can impact the reproductive system by interfering with the hypothalamic‐pituitary‐gonadal (HPG) axis. While in vitro testing methods have been developed to screen chemicals for endocrine disruption, extrapolation of in vitro response to in vivo action shows inconsistent accuracy. We describe here our tissue co‐culture of the fathead minnow (Pimephales ...
With the global decline in the use of polybrominated diphenyl ethers (PBDEs), demand for alternative flame retardants, such as triphenyl phosphate (TPP), has increased substantially. TPP is now detected in various environments including aquatic ecosystems worldwide. However, studies on the toxicological consequences of chronic TPP exposure on aquatic organisms are scarce. We used the zebrafish ...
This paper reports on short‐term fish reproduction assays in zebrafish and fathead minnow conducted to examine the potential for methyl tertiary butyl ether (MTBE) to cause effects on the endocrine system. Both studies were performed under Good Laboratory Practice and in accordance with OECD and USEPA test guidelines. Results of the first study demonstrated that exposure to a high test ...
A modified tier 1 EDSP 21‐day fish short‐term reproduction assay (FSTRA) was used to evaluate the effects of sediment exposure from freshwater and brackish ponds in Bermuda on reproductive fecundity and endocrine function in fathead minnow (pimephales promelas) and killifish (fundulus heteroclitus). Reproductively‐active male and female fish were exposed to control sediment and sediment from ...
The endocrine responses in male Murray rainbowfish (Melanotaenia fluviatilis) have been evaluated after exposures to biologically active concentrations of the non‐steroidal pharmaceutical, flutamide. Fish were exposed to nominal concentrations of 125, 250, 500 and 1000 µg/L of flutamide for 7 days, after which plasma vitellogenin concentration, brain aromatase activity and hepatic expression ...
Mercury can disrupt the endocrine systems of mammals and fish, but little is known about its effects on avian hormones. We employed an experimental manipulation to show that methylmercury suppresses the stress‐induced corticosterone response in birds, an effect previously unreported in the literature. Corticosterone regulates many normal metabolic processes, such as the maintenance of proper ...
Great concern has been raised over the potential impact of environmental contaminants on fish populations that inhabit in the Three Gorge Reservoir (TGR). In the present study, we investigated the endocrine disrupting effects of di‐(2‐ethylhexyl)‐phthalate (DEHP), on the Chinese rare minnow (Gobiocypris rarus), an endemic fish distributing upstream waters in the Yangtze River. Adult rare ...
The U.S. Environmental Protection Agency (EPA) issued its final list of chemicals in the first group of substances that will be screened under the Endocrine Disruptor Screening Program (EDSP).1 Development of this list caps a long, thoughtful, and arduous administrative process that spans over a decade. This “Washington Watch” column briefly reviews the development of the program, with emphasis ...
Received for publication October 29, 2007. The naturally occurring hormones, such as 17-β-estradiol, 17-{alpha}-estradiol, and estrone, present in livestock manure may have detrimental environmental effects if released into surface waters. In areas where manure application is intensive, estrogens have been found in surface waters in concentrations known to affect the endocrine system of fish ...