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Colitis Uc Articles & Analysis
3 articles found
Cytokines in Inflammatory Bowel Disease (IBD) IBD, chronic gastrointestinal inflammation encompassing Crohn's disease (CD) and ulcerative colitis (UC), results from imbalanced interactions between mononuclear phagocytes, Foxp3+ Treg cells, B cells, and cytokines from intestinal epithelial cells (IECs) and immune cells. ...
Furthermore, TNF-a represents the most validated clinical target for ulcerative colitis (UC) and inflammatory bowel diseases (IBD) with multiple emerging neutralizing/inflammation-reducing therapeutics targeting this cytokine for inactivation. ...
A major clinical and research focus is IBD, which is a broad term encompassing ulcerative colitis (UC) and Crohn’s disease (CD), as it effects a significant portion of the population, yet few treatments have been discovered. The etiology of UC and CD are unknown, but major factors, including genetics, diet, microbiome, and environment, have ...