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Immune Suppressing Articles & Analysis
5 articles found
For instance, sphingolipids in exosomes are implicated in cancer progression by promoting exosome-mediated signaling that enhances tumor cell proliferation and immune evasion. Researchers have found that alterations in exosomal lipid profiles can be a hallmark of disease. ...
Mouse models play a pivotal role in this field, as their immune system shares many similarities with that of humans. A key aspect of studying the immune system involves analyzing cytokines, chemokines, and growth factors—molecules that regulate immune responses and influence disease progression. ...
Ly6c+ cells serve as targets for treating IBD, and the immune-suppressive cytokine IL-10 has been reported to inhibit IBD. To induce long-term IL-10 production, IL-10 mRNA-loaded LNP was first prepared, followed by incubation with anchored secondary scFv enabling targeting (ASSET) micelles at 4°C for 48 hours and subsequent incubation with anti-Ly6c ...
This orchestrated strategy affects various dimensions of the immune response. Given its multifaceted contribution to tumor advancement as an emerging immune checkpoint, CD73 stands out as a promising target for cancer treatment. ...
As Th1, Th2, and Th17 responses are involved in the pathogenesis of AD,8,10,14 oral administration of KBL382 modulated the adaptive immune response, leading to suppression of Th1 (IL-2 and IFN-γ), Th2 (IL-4, IL-5, IL-13, and IL-31), and Th17 (IL-17A) cytokines (Figure 5A-E, G-H, and S2C-E). ...
