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Injectable Doses Articles & Analysis
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For example, PEGylated interferon-α (Pegasys® and PegIntron®) shows a 5-10-fold longer half-life than its non-PEGylated counterpart, allowing weekly dosing instead of daily injections. 2. Reduced Immunogenicity PEG masks antigenic epitopes on therapeutic proteins, minimizing antibody-mediated neutralization. ...
It is used to adjust the viscosity and consistency of the vaccine, making it easier to inject and ensuring consistent dosing. Glycerin also helps improve vaccine stability, enhancing its shelf life and storage conditions. ...
The aim of this project is to develop low dose IL-2 for treatment of early onset juvenile Type I diabetes. Low dose injectable IL-2 in animal models has been shown to restore the balance between regulatory and effector T cells and, in this way, can help to reverse autoimmunity and the development of type I diabetes. ...
It was also observed in a study that while the photothermal macromolecular delivery enhancements were similar for the two systems when dosed by optical density, the tumoral uptake and biodistribution profiles for each of these shapes differed, with the nanocages residing in the liver, kidneys and spleen for less time than the nanorods. Additionally, it was observed that the ...
Their novel, patented platform technology replaces subcutaneous or IV injection of biologics with oral dosing. The RaniPill capsule is an orally ingestible vehicle, approximately the size of a standard fish oil or calcium pill, which is designed to automatically administer a precise therapeutic dose of medication upon deployment in the small ...
Rani Therapeutics offers a breakthrough capsule, the RaniPill which could change the way patients with chronic conditions take medication by eliminating the need for painful injections. Rani Therapeutics is a clinical-stage biotherapeutics company offering an alternative to painful injections for patients with chronic conditions such as neuroendocrine ...
Rani, A Platform Technology Company: Rani's proprietary platform technology, the RaniPill capsule, intends to replace subcutaneous or intravenous injections of biologics with oral dosing. RaniPill helps convert injectable biologic drugs such as TNF-alpha inhibitors, interleukin antibodies and basal insulin, among others, into pills. "Our ...
Considerable investment into cancer research has led to the development of remarkable new therapies, which have greatly improved therapeutic outcome for the countless individuals diagnosed with cancer. Until recently, almost all therapies that were granted clinical approval were small molecules. However, biotechnological advances in the last several decades have made it possible to develop ...
Auto-injectors, drug delivery medical devices that automatically administer an injectable dose for a patient, have grown in popularity over the past decade. ...
Beginning in April 1, 2016, they were each injected with three doses, one month apart, of the vaccine. Halford first tested the vaccine on mice, guinea pigs, himself, and co-founder Fernandez. Though neither of them were infected with herpes, they injected themselves to prove their belief that the vaccine was safe. Next came the trial, which not ...