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Metabolic Dysfunction Articles & Analysis
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Nicotinamide adenine dinucleotide (NAD) and its reduced form (NADH) are essential coenzymes involved in a wide array of cellular metabolic processes. As critical mediators in oxidation-reduction (redox) reactions, NAD/NADH plays a pivotal role in energy production and cellular metabolism. ...
HFpEF patients are likely to have a high prevalence of cardiovascular and non-cardiovascular comorbidities, such as obesity, metabolic syndrome, diabetes mellitus type 2, salt-sensitive hypertension, atrial fibrillation (AF), chronic obstructive pulmonary disease, anaemia, and renal dysfunction.[6.7,8] As life expectancy and comorbidity rates rise, the ...
In addition, in mice, a high-sugar diet can lead to cerebrovascular disease, impaired glucose uptake, and higher brain dysfunction associated with psychiatric disorders, and aspirin administration can prevent these high-sugar diet-induced abnormal behavioral phenotypes. ...