Aldevron, LLC products

In Stock, Royalty-Free, Helper Plasmid Solution for Recombinant AAV Manufacturing. Triple transfection is the most common method for rAAV production and does not require co-infection with adenovirus; a helper plasmid provides adenoviral genes. Aldevron`s pALD-HELP has several advantages: Immediately available at research grade and GMP-Source Royalty free, including for commercial products. Replaces any rAAV helper plasmid. Kanamycin resistance. Consistent, reliable supply.

Recombinant AAV (rAAV) manufacturing is comprised of four main parts which include a rep/cap plasmid, a helper plasmid, an expression plasmid, and a viral packaging cell line. Triple transfection of the three plasmids into HEK293 cells is the most frequently used rAAV production method. Aldevron now offers reporter plasmids and cloning vectors specifically for rAAV manufacturing.

Recombinant AAV (rAAV) manufacturing is composed of four main parts which include a rep/cap plasmid, a helper plasmid, an expression plasmid, and a viral packaging cell line. Triple transfection of the three plasmids into HEK293 cells is the most frequently used rAAV production method.

In Stock, Royalty-Free, Helper Plasmid Solution for Recombinant AAV Manufacturing. Triple transfection is the most common method for rAAV production and does not require co-infection with adenovirus; a helper plasmid provides adenoviral genes. Aldevron`s pALD-HELP has several advantages: Immediately available at research grade and GMP-Source Royalty free, including for commercial products. Replaces any rAAV helper plasmid. Kanamycin resistance. Consistent, reliable supply. With Aldevron`s pALD-X80, clients do not need to manufacture a custom batch of the helper plasmid as Aldevron maintains it as an in-stock product, reducing timeline and cost.