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Adrenomedullin and Related Peptides
Proadrenomedullin N - terminal 20 peptide, PAMP (1 - 20) ARLDVASEFRKKWNKWALSR - NH3
PAMP (1-20) is a biologically active molecule produced by posttranslational processing of proadrenomedullin. This peptide is found in a variety of tissues and exerts important biological activities through specific cell surface receptors. PAMP (1-20) is involved in many physiological processes, including vasodilation, bronchodilation, hormone secretion, cell migration, apoptosis, and angiogenesis. This peptide has been implicated in the pathophysiology of several diseases such as renal and cardiovascular disorders, stroke, cancer, and diabetes.
