Krishgen Biosystems products

Tumor necrosis factor alpha (TNF ±) is a multifunctional cytokine secreted primarily by macrophages, natural killer (NK) cells, and lymphocytes.The main function of TNF Alpha is to regulate the immune cells. It has the ability to induce a fever, speed up cell death, create inflammation etc.  It stimulates the acute phase response on the liver, which can lead to a growing amount of C-reactive protein in this organ. Furthermore, TNF functions to bring about insulin resistance, which prevents blood sugar levels from properly decreasing.When concentration levels of TNF are increased, it leads to inflammation signs such as swelling, pain, and redness. Abnormally high levels of TNF have also been linked to a wasting syndrome that causes the body to drastically lose weight at an unhealthy rate. This is often common in cancer patients.Therefore, many inflammatory diseases have been treated by using a TNF inhibitor.