Medosis products

Biongraft offer bone graft substitutes based on Beta Tricalcium Phosphate (b-TCP) augmented with ZrO2 nanoparticles to enhance antibacterial properties. The implants are characterized by a porous architecture and microporosity facilitating capillary action of blood and body fluids. This structure supports enhanced penetration of osteogenic cells and ossification within the synthetic matrix. For structural integration, Biongraft Granules and Sticks exhibit macroporosity that allows deep bone cell invasion, with particle sizes varying from 0.25 mm to 2 mm to promote mechanical interlocking. These materials are 100% synthetic, osteoconductive, biodegradable, and radiopaque. Indicative of their osteoinductive nature, new bone formation is observed within two months post-implantation. Applications encompass ridge augmentation, sinus lifts, and alveolar bone regeneration. Biongraft products are designed to meet the precise specifications required for effective dental surgeries and bone repair, maintaining integrity in complex osseous environments.

Biongraft Flex is an advanced bone graft substitute designed primarily for dental applications, comprising beta-tricalcium phosphate (b-TCP) and a resorbable PLA-based synthetic polymer. This material gradually degrades to harmless byproducts, specifically carbon dioxide and water, facilitating a seamless integration with human physiology. The micro and macro porous architecture is crafted to mimic the structure of natural bone, enhancing osteoconductivity and supporting new bone formation. When applied in dental procedures such as ridge augmentation and sinus lifts, Biongraft Flex promotes the deposition and ingrowth of bone cells, ultimately being replaced by healthy bone tissue. This 100% synthetic and biodegradable solution provides ease of application and can be applied directly or mixed with bone marrow aspirate or blood. It is available in various flexible strip sizes, ensuring versatility to meet specific surgical needs.

The Biongraft Barrier Membrane is crafted for periodontal restorative surgeries to aid bone and periodontal tissue regeneration. Composed of a synthetic poly(lactic acid) (PLA) polymer known for its biocompatibility and bioresorbability, it features a fully resorbable profile, breaking down within 15-20 weeks post-implantation. This material mitigates any risk of disease transmission by avoiding human or animal tissues. The external membrane surface, made of non-porous PLA, prevents epithelial cell and fibroblast intrusion, while the porous internal layer enhances adhesion and differentiation of mesenchymal stem cells. It is applicable in procedures like ridge augmentation, sinus lifts, and alveolar bone regeneration, supporting osseous defect remediation without requiring membrane removal due to its complete bioresorption.

Biongraft Dental Injectable Putty is a vital innovation in the field of bone grafting, primarily developed for dental applications. It is composed of a hydrogel and Beta-tricalcium Phosphate (β-TCP) matrix, enhanced with ZrO2 nanoparticles to provide antibacterial properties. The material serves as an osteoconductive scaffold, facilitating the growth and fusion of surrounding bone tissue in osseous environments. This biocompatible material acts as a bone void filler, designed to be gradually resorbed and replaced by the natural bone during healing. Packaged in a convenient, pre-loaded syringe, the putty requires no mixing, can be applied directly, and is easily molded by hand. It finds applications in alveolar bone regeneration, sinus augmentation, and guided bone regeneration, ensuring effective outcomes in rebuilding skeletal structures. The product's effectiveness is demonstrated by complete tissue regeneration within five months post-application, supporting successful dental implants.