Montana Molecular products

The Borealis Arrestin Biosensors by Montana Molecular represent a cutting-edge tool in the realm of GPCR drug discovery, focusing on arrestin recruitment and signaling dynamics. These biosensors facilitate the continuous measurement of signaling activities in live cells, crucial for the development of precise pharmacological agents. The sensors are designed to work seamlessly with GraphPad Prism software, allowing for easy conversion of time course data into actionable insights. They offer robust Z' values in HEK293T cells and are supported by a plethora of receptor-specific kits for a wide range of GPCR pathways including Gs, Gi, Gq, and arrestin pathways. Additionally, these biosensors can be miniaturized to a 384-well format, supporting multiplexing with other sensors like cAMP, DAG, and Calcium, thereby providing comprehensive insights into the cellular signaling landscape critical for drug development.