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When cellular oxygen levels change, the first response is metabolic: a response that rapidly translates into physiological changes. The central event for metabolic activity in most cells is mitochondrial oxidative phosphorylation, both in ATP production and oxygen consumption. ...
ByBaker
Clone APN1464 recognizes cell surface CD13 antigen, a 150kDa membrane glycoprotein. The CD13 antigen is highly expressed mostly on myeloid-derived hematopoietic cells including granulocytes, monocytes, mast cells, and GM-progenitor cells. CD13 abundantly expresses on most of the malignant cells of myeloid origin such as AML, CML and also on smaller subset of cancer cells of lymphoid origin. ...
An experiment consists of the treatment plates for all of the strains used, doses, number of replicates and metabolic activation. The program is structured to allow concurrent strain-specific positive and negative (solvent and untreated) Controls with or without metabolic activation to be shared between different experiments ...
Mutagenicity Genetic Toxicity in Vitro: Ames: (salmonella typhimurium, Metabolic Activation: with/without) Positive and negative results were reported. ...