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Clone CF-1D12 recognizes human CD52, a 21-28 kDa glycoprotein whose C-terminus is glycophosphatidylinositol (GPI) anchored within the membrane. It is also known as Cambridge pathology antigen 1 (CAMPATH-1). Binding of CF-1D12 with CD52 induces a potent complement-mediated cytolytic immune response of matured lymphocytes. It is widely expressed on the surface of thymocytes and mature lymphocytes, ...
Humanization percentage, CDR Immunogenicity, Antigen binding affinity, Antibody expression level, Aggregation potential, Antibody stability, Heterogenicity. ...
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell ...
