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And as we work to understand cancer, analyzing DNA methylation has come to play an increasingly important role, providing more meaningful information on tumorigenesis, tumor progression and metastasis. Malignant tumors exhibit abnormal DNA methylation - following a pattern differing significantly from that of healthy tissue - at a very early ...
SRSLY NGS library preparation with twist exome panel enrichment for ctDNA SNP profiling. Cell-free DNA (cfDNA), found circulating in blood, originates predominantly from dying cells. In healthy individuals the vast majority of cfDNA derives from hematopoietic myeloid and lymph cells undergoing apoptosis. However, in individuals with cancer, a variable fraction of the cfDNA derives from tumor ...