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Cultures based on cell monolayers have the advantage of reducing tissue complexity to a minimum. However, the lack of normal physiological cell-matrix interactions leads the cell metabolism and gene expression towards a dedifferentiated state. Compared to a monolayer, three-dimensional cultures are associated with a higher cell density, and nutrient supply depends on diffusion through the ...
He is a member of the Canadian Society of Exercise Physiology, the Canadian Physiological Society, and the Canadian Nutrition Society. Editorial Office: apnm@nrcresearchpress.comSubscription Office: nrcresearchpress-csp@subscriptionoffice.comMedia Sales: mediasales@nrcresearchpress.comwww.nrcresearchpress.comApplied Physiology, Nutrition, and ...