t-standard-polystyrene-disposable-cell Downloads
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Item # A-100-T, Standard Polystyrene Disposable CellList Price $41.87Standard Polystyrene Disposable CellSpectrocell disposable cells are of exceptional quality for their type. They are priced to be truly disposable. All 100 ...
ProT2® MHC Class II Tetramers track antigen-specific CD4+ T cells with the most comprehensive class II tetramer catalog range now also available for H-2 IAb, IAd, IAg7. ...
GEXSCOPE Single Cell V(D)J Kit enables simultaneous detection of T-cell or B-cell receptor gene expression, together with whole transcriptome expression at single-cell level. ...
The adaptive immune system plays an extremely important role in fighting against pathogens and cancers as well as protecting the body. The basis of the adaptive immune system is fundamentally dependent on the great diversity of T-cell receptors (TCRs) and B-cell receptors (BCRs) that recognize epitopes from a large variety of exogenous antigens and endogenous factors. ...
Multiplex ALL-1 probe is a multicolored chromosome mix which consists of six chromosomes labeled with a predominant color scheme. Telomeres and pericentromeric regions on each chromosome are labeled with spectrally distinct fluorochrome. The mix is viewed three chromosomes at a time using dual filters. This design detects all numerical and structural abnormalities related to B- and T-cell Acute ...
EXS21546 is our peripherally-restricted and selective antagonist of the Adenosine A2a Receptor. It is designed for anti-cancer immunotherapy, combatting adenosine related immunosuppressive effects, through T-cell ...
MHC class I related protein (MR1) molecules are non-polymorphic, non-classical major histocompatibility complex (MHC) molecules that are highly conserved across many mammalian species. The ligand binding groove of the MR1 molecule has been shown to bind small molecules derived from microbial riboflavin biosynthetic pathways and present these to mucosal associated invariant T cells (MAIT cells). ...
Background: CD11c is expressed by dendritic cells, monocytes, macrophages, neutrophils, and some B cells. CD11c is one of four β2 integrins along with CD11a, C11b and CD11d. CD11c is a receptor for fibrinogen and functions in chemotaxis and cell adhesion. Integrins mediate myeloid cell recruitment from the blood vessels into tissue and lymph nodes and contribute to the immunological synapse ...
LIAISON® LymeDetect® is an innovative approach to EARLY Lyme disease diagnostics that combines assays measuring B cell response, LIAISON® IgG and IgM CLIA assays, and T cell response with the patented QuantiFERON® IGRA technology. This new diagnostic solution has demonstrated a significant improvement in sensitivity vs standard two-tiered testing (sTTT) in the first 21 days of the ...
ByDiasorin
Recently, ex vivo enrichment protocols based on the use of MHC class I tetramers that allows the detection and characterization of rare antigen-specific CD8+ T-cell populations as well as an estimation of their frequency has been reported. Vaccine development would be largely influenced by this ...
T cells play essential roles in adaptive immune responses to viruses, bacteria, parasites, tumors, transplanted tissues, allergens and even to self antigens. Applications for using pMHC tetramers are rapidly expanding and include exciting new possibilities for ex vivo cell expansion and for ...
The adaptive immune system plays an extremely important role in fighting against pathogens and cancers as well as protecting the body. The basis of the adaptive immune system is fundamentally dependent on the great diversity of T-cell receptors (TCRs) and B-cell receptors (BCRs) that recognize epitopes from a large variety of exogenous antigens and endogenous factors. ...
CellGenix TCM is optimized for serum-free expansion and cultivation of T cells. It has been optimized and verified with CAR T cell protocols. In addition, it supports expansion of other cell types such as Treg and iNKT cells. We offer the cytokines and growth-factors needed for optimal growth separately. This gives you the freedom to customize and create your own optimal cytokine mixture. ...
MHC Tetramers have emerged as an important tool for characterization of the specificity and phenotype of T cell immune response, useful in a large variety of disease and vaccine ...
Interleukin 2 (IL-2) is a monomeric cytokine that was originally identified as a T cell growth factor (Gaffen & Liu). It binds to heterotrimeric receptors consisting of CD25, CD122, and CD132. Upon binding, it activates JAK3-, STAT5-, and AKT-dependent signaling pathways, which results in cellular proliferation and survival (Ma et al.). The majority of IL-2 is secreted by activated CD4+ and ...
MHC tetramers allow for ex vivo selection and proliferation of T-cells specific to tumor-related antigens, which can then be reintroduced to augment the immune system. Cancer immunotherapy would be largely influenced by this ...
T cells play critical effector and regulatory roles in adaptive immune responses to bacteria. And MHC Tetramers have been proved to be very effective in identifying antigen-specific T cells by flow cytometry, even those present at low frequencies in fresh populations of lymphocytes sampled directly ex ...
Background:Arginase-1 is expressed by liver cells, myeloid-derived suppressor cells (MDSCs), macrophages, and neutrophils. In mammals, there are three enzymes that metabolise arginine: two arginase isoforms (ARG1, ARG2) and inducible nitric oxide synthase (iNOS). Arginase-1 catalyzes the breakdown of L-arginine into L-ornithine and urea as the final step in the urea cycle. L-arginine is a ...
The antibodies used to stimulate T cell activation via interaction with co-stimulatory receptors on the effector cells can be cross-linked via binding to FcγRIIb receptors on CHO-K1 cells. Based on the properties of the antibody tested, the Co-Stimulatory Immune Checkpoint (i.e., OX40, CD40, GITR and 4-1BB) bioassays can be conducted in a single genetically engineered cell system or dual ...
IMDM(Iscove’s Modified Dulbecco Medium)is an improved DMEM medium, which is used for the culture of erythrocyte progenitor cells and macrophages. The IMDM medium was supplemented with selenium, HEPES, sodium pyruvate and additional amino acids and vitamins on the basis of the DMEM medium, and potassium nitrate instead of iron nitrate, which is suitable for the rapid proliferation, ...