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Cluster of Differentiation 45 (CD45) pHRP Anti-Human Staining Kit immunohistochemistry (IHC) reagent is for use on frozen and formalin-fixed-paraffin-embedded tissues. The CD45 antigen is a protein which was originally called Leukocyte Common Antigen and recognizes an antigen found on lymphoid cells. Anti-CD45 antibody is a useful tool for identifying tumor cells of lymphoid origin. ...
Further mutations may occur in the progeny of the cancer cell, leading to the development of tumour cell invasion and metastasis. The application of NGS provides a high-resolution and global view of the cancer genome in a high throughput manner, revealing several novel cancer-related genes and pathways. ...
ML8500 is an automatic biomedical illumination kit that works seamlessly with Modulight’s ML7710 biomedical laser or optional internal ML6600 series lasers. Modulight customers are using our in-vitro products as their everyday tools helping with their research by providing controlled and repeatable illumination. Read an application note about in-vitro cell viability and dose escalation ...
ISET®, Isolation by SizE of Tumor Cells, is based on the antibody-independent whole blood filtration approach for CTCs and micro-emboli isolation. The solution relies on the larger size of all types of CTCs as compared to the majority of leukocytes. ISET system successfully captures CTCs that are presenting, by definition, heterogeneous phenotypic profiles ...
Our ClearCell FX1 System is a fully automated device for cell retrieval that can separate and enrich wholly intact and viable circulating tumour cells, or CTCs from small amounts of blood. It is driven by our CTChip®FR1 biochip, which is a single-use microfluidic biochip. ...
BriaCell Therapeutics Corp. is a clinical stage immunotherapy company developing treatments that boost the ability of the body’s own cancer-fighting cells to destroy cancerous ...
Exosomes can affect cell functions by transferring substances such as nucleic acids, proteins, and lipids between cells. For example, they play an important role in the process of antigen presentation in antigen-presenting cells, in the development of tumor cells, and in signal transduction in nerve cells. ...
The IsoFlux System enriches intact rare cells from biological samples and prepares them for further analysis. It gives you immediate access to high quality, viable cells in a high-density format, ready for use in the application of your choice. For use with IsoFlux Enrichment Kits containing micro-fluidic cartridges for rare cell ...
Cancertrack is an advanced non-invasive blood test which provides real time intel on the status of a malignancy from a safe, simple and quick blood draw. Cancertrack profiles molecular features in circulating tumor DNA and circulating tumor RNA and also evaluates ‘Circulating Tumor Cells’ (CTCs). ...
Fully integrated imager for automated scanning and detection of CTCs from the IsoFlux System. The IsoFI jx Cytation™ Imager is designed specifically for CTC (circulating Tumor cell} enumeration and protein detection by fluorescent imaging. Based on the industry-leading Cytation imagers from BioTek Instruments, Inc., the IsoFlux Cytation Imager comes pre-configured with the filters, ...
Our ADP-A2M4 (MAGE-A4) SPEAR T-cell therapy is directed to a member of the MAGE family of cancer testis antigen expressed in a number of solid tumor cell types. The MAGE- A4 antigen is among the most commonly expressed cancer-testis antigens. We are conducting various trials with the ADP-A2M4 SPEAR T-cell in various solid ...
The Spotlight EGFR Liquid Biopsy NGS Pathway Panel offers contiguous coverage of EGFR and hotspot coverage of BRAF, KRAS, and NRAS, using a 17-amplicon design to generate multiplex libraries compatible with lllumina sequencing platforms. The Spotlight EGFR Pathway Panel is compatible with short DNA fragments from both cfDNA and FFPE samples. This panel is especially well-suited for research ...
CD133 antigen, also known as prominin, is a trans-membrane glycoprotein. It is a stem cell marker frequently found on multi-potent progenitor cells and is considered to be a cancer stem cell marker which can be detected by Flow ...
Focusing initially on breast cancer, BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW) (TSX:BCT) is dedicated to enhancing the lives of people with cancer with limited therapy options by developing novel immunotherapies to fight cancer. Immunotherapies have become the forefront of the cancer treatments because they use the body’s immune system to destroy cancer cells, offer the potential ...
Clone APN1464 recognizes cell surface CD13 antigen, a 150kDa membrane glycoprotein. The CD13 antigen is highly expressed mostly on myeloid-derived hematopoietic cells including granulocytes, monocytes, mast cells, and GM-progenitor cells. CD13 abundantly expresses on most of the malignant cells of myeloid origin such as AML, CML and also on smaller subset of cancer cells of lymphoid origin. ...
Chemo-scale is an advanced non-invasive test which provides therapeutically relevant information and is based on a safe, simple, and quick blood draw. Chemo-scale™ investigates in vitro chemo-resistance in Circulating Tumor Associated Cells (CTACs) isolated from the blood sample. CTACs include cancer cells that escape from the tumor and enter the bloodstream (circulating tumor cells, CTCs) ...
Indica Labs’ Highplex FL module allows for simultaneous analysis of an unlimited number of fluorescent markers in any cellular compartment – nucleus, cytoplasm, and/or membrane. With the option to define specific cell phenotypes according to marker positivity, this module is ideally suited for applications in immuno-oncology where multiple markers are required to characterize ...
Circulating tumor cells (CTCs) and cancer-associated macrophage-like cells (CAMLs) provide a minimally invasive alternative to tissue biopsy to determine cancer therapy and monitor treatment response and recurrence [Adams, et al., PNAS 2014; Adams, et al., Cytometry 2014]. Cancer associated cells collected on CellSieveTM microfilters are applicable for companion diagnostics and drug development. ...
SRSLY NGS library preparation with twist exome panel enrichment for ctDNA SNP profiling. Cell-free DNA (cfDNA), found circulating in blood, originates predominantly from dying cells. In healthy individuals the vast majority of cfDNA derives from hematopoietic myeloid and lymph cells undergoing apoptosis. However, in individuals with cancer, a variable fraction of the cfDNA derives from tumor ...
Cluster of Differentiation 45 (CD45) pHRP Anti-Human Staining Kit immunohistochemistry (IHC) reagent is for use on frozen and formalin-fixed-paraffin-embedded tissues. The CD45 antigen is a protein which was originally called Leukocyte Common Antigen and recognizes an antigen found on lymphoid cells. Anti-CD45 antibody is a useful tool for identifying tumor cells of lymphoid origin. It is ...