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Lung Capacity Articles & Analysis
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Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by progressive scarring of the lungs, which severely impairs lung function over time. Developing effective treatments for IPF has been a challenge for the medical community, as the mechanisms driving this disease are complex and not fully understood. To accelerate drug discovery, animal models that closely mimic the ...
The rise of antibiotic-resistant bacteria has driven renewed interest in alternative treatments, including phage therapy. A recent study by Yang, F., et al (2024) explores the potential of bacteriophage therapy for treating multi-drug resistant Mycobacterium tuberculosis (Mtb) infections using humanized mouse models. This study highlights the efficacy of phage DS6A in reducing Mtb load ...
In the realm of pulmonary research, the search to understand complex lung conditions has led to the development of various animal models. Among these, a new murine model from Tsijis et al stands out for its potential to investigate flow-induced pulmonary hypertension (PH) and compensatory lung growth (CLG). This blog outlines this innovative model, its ...
The Zephyr Valve is a minimally invasive treatment option that can deliver significant benefits to patients including improvements in lung function, exercise capacity, and quality of life.1 Placed by bronchoscopy, with no cutting or incision, the valves are for patients who remain symptomatic despite optimal management including medications, pulmonary ...
Our differentiated device technology platform has the potential to simplify the delivery of higher efficiency inhalation drug products, making effective therapies available for patients with compromised lung function.” About Nob Hill Therapeutics: Nob Hill Therapeutics patented DryNeb™ Dry Powder Nebulizer is proven to deliver treatment drugs to the lower respiratory ...
The SBIR grant award further validates the potential benefit of this delivery technology to develop therapies to treat severe lung infections.” “This grant is built on our successful phase I grant work conducted a year ago, which delivered encouraging animal efficacy study results. ...
In addition to greatly reducing severe asthma attacks and improving lung function, patients in our clinical trials also reduced their oral corticosteroid use. ...
It is not inconceivable that we will stop conducting lung function tests and perform a CT scan instead to determine lung capacity, residual volume, flow characteristics, and emphysema score. ...
ByFluidda
“We also look forward to expanding our inclusion criteria for ESTRELLA in the near-term to include patients on augmentation therapy – a key area of interest to us as patients with the liver manifestation can also present with AAT deficiency-associated lung disease.” The Phase 1 trial was designed to evaluate the safety, tolerability, pharmacokinetics and ...
CT images were evaluated by Functional Respiratory Imaging with automated tissue segmentation algorithms of the lungs and pulmonary vasculature. The diffusion capacity of carbon monoxide (DLCO) was obtained. ...
ByFluidda
EasyOne spirometers are popular among pulmonologists and medical researchers as they are of the most sensitive devices available, delivering reliable, real-time lung function results and diagnosis of chronic lung diseases, even at the point of care. ...
Fears of a potential heart attack were quickly dismissed and replaced by new concerns over a growth discovered on his lung. The article discusses the process of discovery that lead to a diagnosis of a fungal infection from Coccidioides immitis. The infection reduced the 39 year old’s lung capacity to that of a 72 year old and lead to a ...