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Introduction We recently sat down with one of our valued customers, Dr Alexis Rossignol (Clean Cells), to discuss his experience with VIPS PRO, our cutting-edge technology designed to streamline and enhance the early stages of cell line development. This interview provides insight into Clean Cells’ quest to automate and increase single-cell seeding while having undisputable proof ...
The SIM service offered by Creative Biostructure includes Ultra-high resolution Fluorescence microscopy imaging service for tubulin in living cells (Green Fluorescence)/ lysosomes in living cells (Deep Red Fluorescence/Orange Fluorescence)/ mitochondria in living cells (Deep Red Fluorescence)/ nuclei in living cells (Deep Red ...
CELLINK and Ossiform will be at the American Society of Cell biology conference, taking place in Boston from December 2nd to 6th, to present Ossi Ink and demonstrate the versatility that this material will provide researchers. ...
ByCELLINK
More and more studies have shown that R-phycoerythrin (R-PE) labeled proteins have broad application prospects in laboratory applications, biopharmaceutical and diagnostic technologies, as well as biological imaging. For cell and molecular biology research, R-PE labeled protein can be used as a biomarker in cellular immune analysis, and can also be used as a ...
It is crucial for the identification of novel biomarkers, the diagnosis of diseases such as Alzheimer's, and the biological analysis of drug development processes.POWCLIN, a subsidiary of FPI's Life Sciences division, has developed its own cell analysis-focused SFLO series of full-spectrum flow cytometers and MSFLO benchtop mass spectrometry flow cytometers. The SFLO series is ...
Analysis and Testing Services Taking advantage of its extensive technical expertise in biochemistry, molecular and cell biology, chemistry, and microbiology, CD Formulation can provide comprehensive, innovative, and timely solutions to help customers quickly complete their drug analysis testing requirements. ...
Lifespin’s advisory board consists of key opinion leaders such as James Rothman (Nobel Laureate in Physiology/Medicine, Sterling Professor of Cell Biology, Yale University, New Haven, CT USA) and other prominent leaders in the relevant fields of study. ...
Lipids are essential to many body functions and serve as the building blocks for living cells. Alfa Chemistry has been an ISO 9001:2015 certified supplier of nearly all forms of lipids and fatty acids and continues to broaden its product lines by adding phospholipids, modified lipids, and functionalized lipids. ...
Mariola Fotin-Mleczek, PhD, is an internationally recognized specialist in the field of immunology and cell biology. For nearly 16 years, she worked for CureVac, the global biopharmaceutical company and took responsibility as Chief Scientific and Chief Technology Officer. ...
ByArdigen
We hope to establish our pipeline products as the preferred combination agents with T cell checkpoint inhibitors and other standard of care therapies.” The Phase 1 expansion phase includes IO-108 monotherapy cohorts and IO-108 combination cohorts with anti-PD-1 antibodies (pembrolizumab or cemiplimab, depending on tumor types). ...
“We look forward to advancing IO-108 into multiple expansion cohorts in specific tumor types as monotherapy and in combination with T cell checkpoint inhibitors.” ABOUT IO-108 IO-108 is a fully human IgG4 monoclonal antibody with high affinity and specificity towards LILRB2 (also known as ILT4). ...
In hematologic malignancies, preclinical studies showed that IO-202 converts a “don’t kill me” to a “kill me” signal by activating T cell killing and converts a “don’t find me” to a “find me” signal by inhibiting infiltration of blood cancer cells. In the context of solid tumors, preclinical data ...
“The comprehensive and quantitative metabolic profiling services will enable pharmaceutical companies in particular to perform a range of precision phenotyping of cell or animal models and patient cohorts. Leveraging Lifespin’s Comprehensive Metabolic Database Lifespin has built one of the largest and most comprehensive databases of metabolic health profiles across ...
This data enables the company to accelerate the global development of IO-108 in multiple expansion cohorts in select cancers as a monotherapy and in combination with T cell checkpoint inhibitors. The IO-108 Phase 1 clinical trial in China (NCT05508100) is currently enrolling patients. ...
Rizo served in a number of oncology drug development functions with increasing responsibilities at Janssen Research and Development, LLC (Janssen), including Senior Director, Compound Development Team Leader for all myeloid assets, Senior Director, Global Clinical Leader for the imetelstat, ibrutinib mantle cell lymphoma (MCL) program, and others. In these roles, she had ...
ByBayer AG
Ubiquitination is one of the most prevalent post-translational modifications (PTMs) in cells. Ubiquitin modification induces protein degradation, which affects the function, localization, and activity of proteins. Therefore, the study of protein ubiquitination plays an important role in cell biology and drug discovery. With the comprehensive ...
ABOUT LILRB2 (ILT4) LILRB2, also known as ILT4, is expressed mostly by myeloid cells, including monocytes, macrophages, dendritic cells, and neutrophils. ...
(Nasdaq: BLI), a leader in digital cell biology, today announced its participation at the 18th Annual PEGS Boston Conference, a protein engineering and cell therapy summit, being held virtually and in person from May 2-6, 2022 at the Hynes Convention Center. ...
The data being presented suggest that LAIR1 antagonist antibodies reverse collagen-mediated immune suppression on T cells and myeloid cells in the solid tumor microenvironment, thereby promoting anti-tumor immunity. ...
This research has rapidly advanced a completely new field of study and class of cancer immunotherapy that goes beyond T cells to overcome immune resistance and the limitations of current treatment options. ...