Cornea Cell Articles & Analysis
4 news found
BRM421 is a first-in-class, innovative drug based on a neurotrophic stem cell regenerative peptide (PDSP). It stimulates stem cell differentiation, repairs the cornea, inhibits inflammation, and promotes recovery in DED. Phase 2 clinical trial results have shown that BRM421 not only significantly improved DED symptoms including dryness, ...
BRM421 is based on BRIM’s proprietary stem cell regenerative Pigment Epithelium-Derived Factor (PEDF) derived Short Peptide (PDSP) technology platform, which underpins several products in its pipeline and has the potential to be effective in multiple therapy areas and indications. The functional domain of PEDF chosen to generate PDSPs can be used to treat dry eye disease ...
The 36-month Phase 2 data also continued to demonstrate a favorable safety profile foriDose TR, with no clinically significant corneal endothelial cell loss, no serious corneal adverse events and no adverse events of periorbital fat atrophy and conjunctival hyperemia reported to date in either elution arm. ...
CIS Pharma’s new lens care patent application was published. The patent covers the latest developments in the field of contact lens care creating multi-purpose disinfecting solutions, MPDS, with an improved efficacy/safety profile. CIS Pharma’s innovation reduces the trade-off between efficacy and safety, inherent to MPDS that cover the complete contact lens care regimen with just one ...