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Degeneration Progresses Articles & Analysis

9 news found

New data from pivotal studies with aflibercept 8 mg

New data from pivotal studies with aflibercept 8 mg

Aflibercept 8 mg was investigated in neovascular (wet) age-related macular degeneration (PULSAR) and diabetic macular edema (PHOTON) to evaluate efficacy and safety compared to Eylea (aflibercept 2 mg). ...

ByBayer AG


Bayer submits aflibercept 8 mg for marketing authorization in Japan

Bayer submits aflibercept 8 mg for marketing authorization in Japan

Submission to the Ministry of Health, Labor, and Welfare (MHLW) in Japan for aflibercept 8 mg in neovascular (wet) age-related macular degeneration (nAMD) and diabetic macular edema (DME) is based on positive results of phase III clinical trials, PULSAR and PHOTON In both trials, aflibercept 8 mg demonstrated unprecedented durability results with treatment intervals of up to ...

ByBayer AG


Bayer submits aflibercept 8 mg for regulatory approval in two major retinal eye diseases in the EU

Bayer submits aflibercept 8 mg for regulatory approval in two major retinal eye diseases in the EU

“Patients with neovascular age-related macular degeneration and diabetic macular edema rely on continuous treatment to maintain their visual acuity and prevent visual impairment or even blindness – but some struggle with adherence. ...

ByBayer AG


Detailed data from pivotal studies with aflibercept 8 mg demonstrate sustained improvements in visual acuity and anatomic measures with large majority of patients maintaining treatment intervals of 16 weeks at week 48

Detailed data from pivotal studies with aflibercept 8 mg demonstrate sustained improvements in visual acuity and anatomic measures with large majority of patients maintaining treatment intervals of 16 weeks at week 48

The phase III PULSAR trial in neovascular (wet) age-related macular degeneration (nAMD) and phase II/III PHOTON trial in diabetic macular edema (DME) respectively met their primary endpoint of non-inferiority of aflibercept 8 mg extended dosing regimens for best corrected visual acuity (BCVA) at week 48, compared to Eylea dosed every 8 weeks, all following initial monthly doses. ...

ByBayer AG


Hyalex receives FDA Breakthrough Device Designation for novel HYALEX Cartilage System

Hyalex receives FDA Breakthrough Device Designation for novel HYALEX Cartilage System

” “The HYALEX Cartilage System is exciting because its biomimetic material properties create the potential to replace a damaged joint surface, and thereby interrupt the progression of cartilage degeneration,” said Dr. Thomas Vail, Professor and Chair of Orthopaedic Surgery at UCSF. ...

ByHyalex Orthopaedics, Inc.


DiscGenics Completes Patient Enrollment in Japanese Clinical Study of Cell Therapy for Disc Degeneration as US Study Achieves One-Year Follow-up Milestone

DiscGenics Completes Patient Enrollment in Japanese Clinical Study of Cell Therapy for Disc Degeneration as US Study Achieves One-Year Follow-up Milestone

“In preclinical observations of IDCT’s human Discogenic Cells in a canine disc degeneration model, I observed their ability to stop disc height degeneration while improving the structure of the intervertebral disc. ...

ByDiscGenics, Inc.


Gelmetix signs collaboration for development of Knee Osteoarthritis product

Gelmetix signs collaboration for development of Knee Osteoarthritis product

These injuries originate mostly from traumas related to physical activity or sports practice and when inadequately treated can lead to progressive degeneration of the cartilage and total loss of joint function, with serious consequences in terms of loss of mobility and decrease in quality of life. ...

ByGelmetix Limited


ALS research gets a $4.1 million boost from CVS/pharmacy fundraising Campaign

ALS research gets a $4.1 million boost from CVS/pharmacy fundraising Campaign

ALS, or amyotrophic lateral sclerosis, is a disorder in which there is progressive degeneration of motor nerves in the brain and spinal cord leading to paralysis and death, typically within three to five years. ...

ByCSRwire - Corporate Social Responsibility Newswire


CVS/pharmacy kicks off 9th annual ALS fundraising Campaign in stores nationwide

CVS/pharmacy kicks off 9th annual ALS fundraising Campaign in stores nationwide

ALS is a disorder in which there is progressive degeneration of motor nerves in the brain and spinal cord leading to paralysis and death, typically within three to five years. ...

ByCSRwire - Corporate Social Responsibility Newswire

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