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Disease Target Articles & Analysis
203 news found
These extracellular vesicles, composed of cell membranes, can attach to target cells through surface adhesion proteins and carrier ligands, such as tetrapeptides, integrins, CD11b, and CD18 receptors, and deliver their payloads. Several studies have shown that, depending on their properties and origin, extracellular vesicles, such as exosomes, have specific cell tropism and can ...
Infectious diseases are disorders caused by organisms — such as bacteria, viruses, or parasites. A vaccine is a specialized biological formulation that triggers the immune system to recognize and activate protective responses against specific disease-causing agents. With the global landscape of infectious diseases continually evolving, ...
Yang, L., et al (2024) introduces LungVis 1.0, an AI-driven imaging platform integrating light sheet fluorescence microscopy (LSFM) and deep learning for mapping nanoparticle (NP) deposition across murine lungs. The research highlights the advantages of aerosol-based delivery methods over traditional liquid-based approaches, emphasizing the uniformity of NP deposition in distal alveolar ...
Pulmonary arterial hypertension (PAH) is a progressive, life-threatening condition characterized by increased pulmonary arterial pressure, vascular remodeling, and persistent inflammation. Despite advances in treatment, current therapies—such as sildenafil, iloprost, and riociguat—primarily focus on reducing symptoms by dilating blood vessels. Unfortunately, these therapies do ...
One of the standout technologies on display was Creative Biolabs' phage display service, which enables the selection of antibodies with high specificity and affinity against a wide range of targets. During the event, the team demonstrated their pipeline from phage construction to screening and their masterpiece in discovering PTM specific antibodies, anti-idiotype antibodies, ...
CD Formulation, a leader in biotechnological innovation, is advancing the field of targeted drug delivery with its customized metal-organic frameworks (MOFs) services. ...
Small molecule drugs have a proven track record of success in treating a wide range of diseases, including cancer, cardiovascular disorders, and infectious diseases. By leveraging the potential of small molecules, our clients can benefit from: Targeted Therapies - Small molecules can be designed to selectively modulate specific biological ...
This breakthrough has opened up new possibilities in treating complex diseases that require targeted therapy or personalized medication. Furthermore, CD Formulation's expertise in formulation development extends beyond drug release kinetics. ...
As several gene therapy approvals for rare disease treatment gain steam in 2023, a comprehensive set of gene therapy development solutions is released to pave richer avenues for rare disease research. This path-breaking move sees the integration of cutting-edge technology with state-of-art research facilities to amplify the possibilities of devising effective ...
AI-Powered Design: CD ComputaBio's state-of-the-art AI algorithms analyze vast datasets of antibody structures and sequences to predict and design novel antibodies with exceptional specificity and affinity. 2. Precision Targeting: The technology allows for the precise targeting of disease-related molecules by understanding the intricate ...
Gaining a deeper understanding of these intricate interactions is essential for deciphering disease mechanisms and identifying potential therapeutic targets. Far-Western Blot Analysis emerges as a powerful tool, allowing researchers to delve into the intricacies of protein networks, uncovering vital information about protein binding partners and unraveling the ...
Mass spectrometry is a powerful analytical tool that plays a key role in drug development by providing accurate, reliable, and timely data for successful clinical trials, disease research, drug development, and target discovery experiments. ...
Mitochondria dysfunction has been tied to a host of diseases, ranging from neurodegenerative ailments, over heart attacks and strokes, to age-related degeneration. "Whilst Mitochondria have been known as disease targets for a long time, treating them has proven challenging", notes Dr. ...
High demand seen for effective disease management platform for second most common cancer in Singaporean men NEW YORK and SINGAPORE, March 28, 2022 /PRNewswire/ -- miR Scientific, a New York-based healthcare company dedicated to transforming global cancer management, and Leonie Hill Capital, a Singapore-based organization focused on large-scale, sophisticated healthcare access and distribution, ...
Based on rich experience in genomic analysis, CD Genomics has developed a specialized platform for targeted sequencing of cancer-related genes to accelerate research on disease pathogenesis, disease identification, biomarker discovery, targeted drug development, etc. ...
(NYSE and TASE: TEVA) and MODAG GmbH today announced a strategic collaboration on the exclusive worldwide licensing and development of MODAG's lead compound anle138b and a related compound, sery433. Anle138b targets pathological alpha-synuclein oligomers and is being evaluated in patients with neurodegenerative diseases for potential disease ...
The vgAAV vector platform, based on novel engineered AAV capsids, enables a superior transduction of target cells and is designed to efficiently cross biological barriers. ...
Currently, there are no treatments for Stargardt disease available. “We are excited that our product candidate VG801 for Stargardt disease is ready for IND-enabling studies. ...
It comprises of pluripotent stem cell-derived dopaminergic neurons that are implanted into the brain, thus taking target at the root cause of the disease. According to the Parkinson’s Foundation, more than 10 million people worldwide suffer from Parkinson’s disease. ...
ByBayer AG
With the support of Inflexion as a minority investor, Proteros aims to further strengthen the company’s footprint in the US both organically and through potential acquisitions, drive sustainable growth across all of its Business Units such as, Cryo-EM, fit for purpose Biologics and Proteins, as well as integrated Discovery Solutions services and further strengthen overall value propositions ...