Drug Evaluation Articles & Analysis
54 news found
In addition to screening, Protheragen-ING AI-Pharma offers advanced AI capabilities for optimizing the chemical structure of drug candidates. The AI-powered system evaluates important characteristics, such as binding affinity and pharmacokinetics, to refine compounds and enhance their therapeutic potential. ...
Developing effective treatments for IPF has been a challenge for the medical community, as the mechanisms driving this disease are complex and not fully understood. To accelerate drug discovery, animal models that closely mimic the human disease are crucial. In this context, a recent study by Petersen et al (2024) has made significant strides in validating a well-known IPF mouse ...
The process of antipsychiatric drug development typically involves several stages, including identifying potential drug targets, conducting preclinical research to test the safety and efficacy of potential drug candidates, and then moving on to clinical trials to further evaluate the drug’s effectiveness ...
“Our extensive portfolio covers a range of pharmacological services essential for the intricate process of veterinary drug development. By offering tailored solutions in pharmacodynamics, pharmacokinetics, toxicology, and consistency evaluation, we endeavors to addresses the multifaceted challenges faced by veterinarians and researchers,” said the ...
CD Formulation is making waves in the pharmaceutical industry with its innovative drug delivery technologies. With a focus on sustained and controlled release formulations, as well as liquid, semi-solid, injectable, and nanoformulations, CD Formulation is at the forefront of the industry's efforts to enhance drug efficacy. One of CD Formulation's key technology platforms is its sustained ...
By conducting comprehensive efficacy evaluations using CD Formulation's advanced formulation techniques, pharmaceutical companies can streamline the drug development process and bring novel treatments to market more efficiently. In addition to enhancing the evaluation of oral thin films, CD Formulation's formulation technology also has the ...
STEMart, a US-based provider of comprehensive services for all phases of medical device development, announced the launch of its new Force Degradation Services to help pharmaceutical and medical device companies evaluate the stability of their drug candidates and finished products under a variety of stress conditions, ensuring their safety and efficacy throughout ...
BySTEMart
Microneedles have emerged as groundbreaking technology in the field of drug delivery, providing a more efficient and painless way of administering medicines. ...
CD Formulation, a leader in the field of pharmaceutical formulation development, has been at the forefront of developing robust and reliable methodologies to evaluate the biocompatibility of various drug delivery systems. In collaboration with renowned research institutions, CD Formulation has created an in vitro cytotoxicity testing platform specifically ...
Microspheres, tiny spherical particles typically ranging from 1 to 100 microns in diameter, offer immense potential for targeted drug delivery. By encapsulating active pharmaceutical ingredients (APIs) within these microspheres, drugs can be delivered directly to specific tissues or organs, resulting in improved therapeutic efficacy and reduced side effects. ...
These services encompass cell-level screening, identification of cell lines and models, genotyping services for rats and mice, PET-CT services, and flow cytometry services. Drug Safety Evaluation Services One of the core services offered by Alfa Chemistry is drug safety evaluation. This critical step in the drug ...
This cutting-edge technology provides scientists and researchers with an innovative platform to study human organs in a way that was previously impossible, promising to accelerate drug discovery, reduce the need for animal testing and ultimately transform the future of medicine. ...
Pre-prescription studies are crucial for the formulation prescribing process, which is important for assessing the drug-forming properties of compounds, selecting the appropriate dosage form, and ensuring quality control for safe and effective drugs. Pre-prescription formulation analysis involves evaluating the chemical and physical properties of ...
The service predicts key parameters such as the interaction modes between molecules, including hydrogen bonds, van der Waals forces, and ionic bonds, as well as binding affinity and complementarity, to help clients better understand the mechanism of drug action and optimize drug molecule design and screening. Small molecule drug development ...
“Our analysis and testing services will support pharmaceutical companies at every step and phase of the drug development lifecycle, making sure the entire drug development process complies with the latest regulatory standards and ...
Sage Therapeutics and Biogen have initiated a rolling submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration for zuranolone in the treatment of MDD and PPD, and plan to complete the NDA filing in the second half of 2022. ...
About the TORCH-2 Trial The TORCH-2 trial (NCT04337463) was designed to evaluate the safety and efficacy of ATG-008 combined with toripalimab (PD-1 antibody) in subjects with advanced solid tumors. ...
In the process of drug development, the evaluation of drug effectiveness is one of the keys to determining whether prodrugs can sufficiently reach the market stage. ...
Food & Drug Administration (FDA) approvals for orally inhaled generic products (OIDPs) via the alternative bioequivalence pathway. Fluidda’s proprietary in silico platform FRI (Functional Respiratory Imaging) delivers quantitative predictions of regional drug deposition in disease state lungs using Computational Fluid Dynamics (CFD). ...
ByFluidda
A post-hoc analysis of the WATERFALL Study in MDD evaluated the statistically significant reduction in depressive symptoms as measured by HAMD-17 at Day 15 as well as rapid onset observed at Day 3 and Day 8 with zuranolone 50 mg compared to placebo suggested that the differences were clinically meaningful according to estimates of minimal important difference. ...