Drug Solubility Articles & Analysis
12 news found
Challenges in Pharmaceutical Development Improving the dissolution, solubility, and bioavailability of poorly soluble drugs (BCS Class 2) remains a significant challenge. Amorphous Solid Dispersions (ASDs) are a promising solution, stabilizing drugs in their amorphous form using polymers and low-molecular-weight excipients. ...
Transdermal Delivery: Overcoming Natural Barriers Traditional transdermal drug delivery has struggled with the skin’s natural barrier, the stratum corneum, which limits effective drug absorption. ...
CD Formulation is making waves in the pharmaceutical industry with its innovative drug delivery technologies. With a focus on sustained and controlled release formulations, as well as liquid, semi-solid, injectable, and nanoformulations, CD Formulation is at the forefront of the industry's efforts to enhance drug efficacy. ...
The design of such drug carriers also helps to overcome some of the limitations of conventional drugs such as biostability, water solubility and drug distribution in the body. ...
Over the past decade, the CD Formulation’s expert team has made tireless efforts in the research and development of drug delivery systems, trying to improve the pharmacokinetics and pharmacodynamics of drugs. ...
Compared with conventional drugs, nanoparticle-based drug delivery has obvious advantages in terms of stability, biocompatibility, permeability, retention effect, and precise targeting. ...
Choosing the most appropriate delivery system has tremendous benefits, including but not limited to controlled release of drugs, enhanced drug targeting, improved solubility and bioavailability of drugs. In the past decade, several new drug delivery systems have been formulated, in the hope to provide promising ...
Though the service portfolio of CD Formulation is far-ranged and nearly covers the whole process of drug formulation, encompassing pre-formulation, formulation, drug analysis, solubility improvement and bioavailability enhancement, packaging, drug delivery system development, one-stop pharmaceutical formulation solution as well ...
Insilico's PCC is a potent and selective MAT2A inhibitor. It demonstrated excellent drug-likeness with good solubility and permeability, good activity at low doses in animal models, and a favorable safety profile in preclinical studies. ...
For researchers who are troubled by insoluble or poorly soluble drugs, CD Formulation is now prepared to avail its capability, helping to find the most appropriate approach to assist their drug development projects “While our scientific team creates new ways to revitalize failed or discontinued products for our clients, we also help to ...
Solubility measurement is a key element for a preliminary understanding of the pharmacodynamic properties of the drug. On August 30, 2021, CD Formulation, a leading CRO service provider in the industry, announces the release of drug solubility analysis, which is an indispensable step in drug development and ...
It is a useful self-assembly reagent that can be used to prepare PEGylated liposomes or micelles, and it also provides thiol or cysteine reactive maleimide groups. It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific ...