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Fatty Liver Disease Articles & Analysis

19 news found

The Effect of Combined Exercise and Diet on Obese Mice

The Effect of Combined Exercise and Diet on Obese Mice

Such fat accumulation can have serious health consequences, raising the risk of chronic diseases like cardiovascular conditions, diabetes, and some cancers. It is usually associated with a higher prevalence of non-alcoholic fatty liver disease (NAFLD) and asthma. ...

BySCIREQ - an emka TECHNOLOGIES Company


Creative Proteomics Metabolomics Expands Service Offering with the Launch of Gut Microbiota Metabolomics Solution

Creative Proteomics Metabolomics Expands Service Offering with the Launch of Gut Microbiota Metabolomics Solution

This service intuitively studies the relationship between gut flora and disease development, providing new ideas for disease prevention and treatment and improving host health. ...

ByCreative Proteomics


Alnylam and Regeneron Report Promising Data from Ongoing Phase 1 Study of ALN-HSD in NASH Patients and Healthy Volunteers

Alnylam and Regeneron Report Promising Data from Ongoing Phase 1 Study of ALN-HSD in NASH Patients and Healthy Volunteers

In the first two Part B cohorts, ALN-HSD was associated with robust target knockdown and numerically lower liver enzymes and biopsy-derived nonalcoholic fatty liver disease (NAFLD) Activity Score (NAS)* over six months in patients receiving ALN-HSD (N=20) relative to placebo (N=4). ...

ByAlnylam Pharmaceuticals, Inc.


Independent Clinical Study Shows Seravue® Has High Sensitivity And Specificity For The Detection Of Liver Cancer In Nafld And Related Cirrhotic Patients

Independent Clinical Study Shows Seravue® Has High Sensitivity And Specificity For The Detection Of Liver Cancer In Nafld And Related Cirrhotic Patients

This study focused on the performance of Seravue and the LC-SPIK biomarker in detecting hepatocellular carcinoma (HCC) in a pool of nonalcoholic fatty liver disease (NAFLD) related cirrhosis patients. Here, LC-SPIK had an AUC of 0.841 and significantly outperformed AFP, the most common biomarker used for HCC detection today. ...

ByImCare Biotech, LLC


Lumos Pharma Announces a Clinical Collaboration with Massachusetts General Hospital (MGH) to Evaluate Oral LUM-201 in Nonalcoholic Fatty Liver Disease (NAFLD) in a Phase 2 Investigator-Initiated Trial

Lumos Pharma Announces a Clinical Collaboration with Massachusetts General Hospital (MGH) to Evaluate Oral LUM-201 in Nonalcoholic Fatty Liver Disease (NAFLD) in a Phase 2 Investigator-Initiated Trial

Dichtel and Massachusetts General Hospital to evaluate LUM-201 in NAFLD,” commented Rick Hawkins, CEO and Chairman of Lumos Pharma. “Nonalcoholic fatty liver disease is estimated to be prevalent in approximately 25% of adults worldwide. ...

ByLumos Pharma


Altimmune Announces Initiation Of 48-Week Phase 2 MOMENTUM Trial Of Pemvidutide In Obesity

Altimmune Announces Initiation Of 48-Week Phase 2 MOMENTUM Trial Of Pemvidutide In Obesity

The Company also today announced the completion of enrollment in its 12-week Phase 1b clinical trial of pemvidutide in subjects with non-alcoholic fatty liver disease (NAFLD). The 48-week MOMENTUM trial is being conducted at approximately 25 sites in the United States with Dr. ...

ByAltimmune Inc.


Sonic Incytes Successfully Completes Series A Raise of US$7.3M to Accelerate VelacurTM Commercialization

Sonic Incytes Successfully Completes Series A Raise of US$7.3M to Accelerate VelacurTM Commercialization

“Their support is based on the recognition that fatty liver disease is a significant health issue and underscores the need for an accurate, accessible and affordable point of care tool to assess patients affected by this often-silent ...

BySonic Incytes Medical Corp.


HemoShear Identifies Second Target to Treat Nash for Takeda

HemoShear Identifies Second Target to Treat Nash for Takeda

In addition, Nature Scientific Reports published the company’s research analyzing gene expression at various stages of nonalcoholic fatty liver disease. NASH, one of the leading causes of transplantation, is a serious, chronic liver disease that is estimated to impact over 16 million people in the United ...

ByHemoShear Therapeutics, Inc.


Velacur Data Presented at 2021 AASLD The Liver Meeting

Velacur Data Presented at 2021 AASLD The Liver Meeting

When measuring fatty liver disease in obese patients, a greater imaging depth (below subcutaneous fat and the liver capsule) results in a more accurate liver health assessment. ...

BySonic Incytes Medical Corp.


Fractyl Health Announces Publication of Pioneering New Model of Intestine’s Role in Metabolism

Fractyl Health Announces Publication of Pioneering New Model of Intestine’s Role in Metabolism

It is this imbalance, which came to the attention of Fractyl Health’s founders, that then led to the company’s pursuit of therapeutic approaches that can potentially correct the hormonal signals from the intestine and stem the tide of metabolic diseases in society. “Within the past three months, we have seen several publications from leading scientists that are ...

ByFractyl Health


Sonic Incytes Showcases Velacur at ACG 2021

Sonic Incytes Showcases Velacur at ACG 2021

With 100 million Americans affected by fatty liver disease, one-fifth will progress to a more severe form of the condition and are at further risk of developing cirrhosis and liver cancer. ...

BySonic Incytes Medical Corp.


Fractyl Announces Tenth Trial Site Opened in REVITA-T2Di Study of Revita DMR for Type 2 Diabetes

Fractyl Announces Tenth Trial Site Opened in REVITA-T2Di Study of Revita DMR for Type 2 Diabetes

DMR Treatment Revita DMR is based on Fractyl’s breakthrough insights surrounding the role of the gut in metabolic diseases. An outpatient endoscopic procedure, Revita DMR resurfaces the lining of the upper intestine (duodenal mucosa). ...

ByFractyl Health


The Ultimate List of Attractive MedTech M&A Targets

The Ultimate List of Attractive MedTech M&A Targets

The product, a non-invasive neurostimulation device using gamma frequency technology, is the first in the company’s pipeline of digital therapeutics for neurodegenerative diseases and other chronic indications. The company also released results from two clinical studies at the Alzheimer’s Disease Parkinson’s Disease Conference ...

ByAnuncia Medical, Inc.


Sonic Incytes Recognized as a Ready to Rocket Company For Second Year in a Row

Sonic Incytes Recognized as a Ready to Rocket Company For Second Year in a Row

“It’s a great honour to be recognized by Rocket Builders for the second year in a row,” said George Aliphtiras, CEO, Sonic Incytes Medical Corp. “Fatty liver disease is an emerging health crisis that affects 1 in 4 people worldwide and, with FDA clearance of VelacurTM, we’re excited to offer health care practitioners ...

BySonic Incytes Medical Corp.


Fractyl Announces First Patient Enrolled in Pivotal Study of Novel Procedural Therapy Revita® DMR for Type 2 Diabetes

Fractyl Announces First Patient Enrolled in Pivotal Study of Novel Procedural Therapy Revita® DMR for Type 2 Diabetes

(Fractyl), a life sciences company dedicated to developing novel therapeutic interventions aimed at reversing the metabolic disease epidemic, today announced the enrollment of the first patient in a pivotal clinical trial of Revita® DMR for patients with type 2 diabetes. ...

ByFractyl Health


Fractyl Announces Publication of Clinical Results from INSPIRE Study Showing Durable Insulin-Free Glycemic Control in Majority of Patients Treated

Fractyl Announces Publication of Clinical Results from INSPIRE Study Showing Durable Insulin-Free Glycemic Control in Majority of Patients Treated

“Eliminating the need for daily insulin could transform disease management for the hundreds of millions of people across the world suffering from type 2 diabetes. ...

ByFractyl Health


Fractyl Raises $55 Million in Series E Financing to Advance Revita DMR for Type 2 Diabetes

Fractyl Raises $55 Million in Series E Financing to Advance Revita DMR for Type 2 Diabetes

” “Fractyl's founding mission was to find a better way to treat type 2 diabetes by addressing the root cause of disease that can reverse the disease process rather than manage its symptoms. ...

ByFractyl Health


Fractyl Announces FDA IDE Approval to Begin Pivotal Study of Revita DMR for Insulin-Treated Patients with Type 2 Diabetes

Fractyl Announces FDA IDE Approval to Begin Pivotal Study of Revita DMR for Insulin-Treated Patients with Type 2 Diabetes

This minimally-invasive, outpatient, endoscopic procedure is a non-drug and non-surgical alternative that has been shown in clinical trials to enhance insulin sensitivity, lower HbA1c, and reduce liver fat to create long-lasting improvements in both blood sugar control and fatty liver disease to help patients with type 2 diabetes ...

ByFractyl Health


New Approaches to the Old Hunt for NASH Therapies

New Approaches to the Old Hunt for NASH Therapies

Non-Alcoholic Steatohepatitis (NASH) is the most severe form of non-alcoholic fatty liver disease (NAFLD). The global prevalence of NAFLD is as high as one billion and is the most common cause of chronic liver disease, affecting between 80 and 100 million in the U.S., among whom nearly 25% progress to NASH. NASH ...

ByGenuity Science

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