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Flare Articles & Analysis

21 news found

Newborn Snoring: causes, effects, and solutions for peaceful sleep

Newborn Snoring: causes, effects, and solutions for peaceful sleep

What is Newborn Snoring? Oftentimes, newborns breathe noisily when they sleep. It may be caused due to extra mucus or dryness in their tiny nasal passages. However, if you notice your newborn baby actually snoring on a regular basis, consult with a doctor. If your snoring is causing issues with your partner or his/her snoring is irritating you at night, it is important that you seek timely ...

ByTannerMedico A/S - Asonor


EPSRC-funded software for research communities project to position OpenMM community at forefront of latest CADD developments

EPSRC-funded software for research communities project to position OpenMM community at forefront of latest CADD developments

This growing demand for training and support can no longer be maintained by the current OpenMM developers, so assistance is needed from the OpenMM community. The Flareâ„¢ structure-based and ligand-based drug design platform has a plugin interface that enables incorporation of cutting-edge third-party software (including OpenMM) to introduce new capabilities. More ...

ByCresset Group


Engineering antibody-antigen interfaces to improve therapeutic properties

Engineering antibody-antigen interfaces to improve therapeutic properties

Changes to residues on the antibody surface will also change the surface electrostatics, something that Cresset Discovery scientists can analyze with ease using Flare™, Cresset’s proprietary molecular modeling platform. ...

ByCresset Group


Galapagos announces CHMP adoption of PRAC’s recommendation for Jyseleca® following extensive safety review of all JAK inhibitors

Galapagos announces CHMP adoption of PRAC’s recommendation for Jyseleca® following extensive safety review of all JAK inhibitors

For at-risk patients with UC, the initiation dose remains unchanged, but a maintenance dose of 100mg should be considered. In case of a flare of disease, the dose should be escalated to 200mg once daily. For long-term treatment in patients with above risk factors, the lowest effective dose should be used. ...

ByGalapagos NV


Leveraging protein DNA/RNA interactions in drug discovery

Leveraging protein DNA/RNA interactions in drug discovery

Careful processing of the complex enables Cresset Discovery modelers to employ the use of computationally more intensive methods like Flareâ„¢ Molecular Dynamics to assess complex structure reliability. ...

ByCresset Group


Grossmont Orthopaedic Medical Group Performs First Meniscus Replacement in San Diego with NUsurface Meniscus Implant

Grossmont Orthopaedic Medical Group Performs First Meniscus Replacement in San Diego with NUsurface Meniscus Implant

As an avid surfer for over 25 years, Marchand went from surfing every day to once per week at best – with the expense of pain flare-ups after each session. His knee became extremely vulnerable to any type of sudden movement, and he was forced to limit all sports activities, including mountain biking, skiing and hiking. ...

ByActive Implants LLC


Aurinia Presents Results from the Two-Year AURORA 2 Continuation Study at the 2022 European Renal Association (ERA) Congress

Aurinia Presents Results from the Two-Year AURORA 2 Continuation Study at the 2022 European Renal Association (ERA) Congress

Secondary endpoints include renal response, renal flare, renal outcomes, and changes in urine protein to creatinine ratio (UPCR) and estimated glomerular filtration rate (eGFR). ...

ByAurinia Pharmaceuticals Inc.


DYV-700 Gout Abstract

DYV-700 Gout Abstract

Theoretically, an alkalinizing agent such as sodium bicarbonate (baking soda) may increase the systemic and/or local pH and may allow pH sensitive uric acid crystals to dissolve resulting in temporary relief of pain and shortening duration of a gout flare, however oral sodium bicarbonate use causes intolerable gastrointestinal side-effects. The objective of this study was to ...

ByDyve Biosciences


Vaccitech reports promising interim efficacy analysis in Phase 1b/2a clinical study in chronic HBV

Vaccitech reports promising interim efficacy analysis in Phase 1b/2a clinical study in chronic HBV

One patient with a decrease experienced a transaminase flare after the MVA boost plus nivolumab that resolved over 3 weeks. ...

ByVaccitech plc


National Psoriasis Awareness Month: Grace`s Story

National Psoriasis Awareness Month: Grace`s Story

I also think having a place to easily track my symptoms would help me better manage my flares and learn how to take care of myself better during bad health days. ...

ByPortal Instruments, Inc.


Accelerating Lupus Drug Discovery & Development - Fireside Chat with Experts in SLE Research

Accelerating Lupus Drug Discovery & Development - Fireside Chat with Experts in SLE Research

These treatments are often unsuccessful in treating the patients — particularly those with a more severe form of the disease — and longer term, these treatments can be associated with several side effects including infections, hepatotoxicity, osteoporosis and more. Episodic flares of symptoms frequently necessitate changes in medications or dosages, further ...

ByGenuity Science


Lilly`s Mirikizumab Helps Patients Achieve Clinical Remission and Improves Symptoms in Adults with Ulcerative Colitis in 12-Week Phase 3 Induction Study

Lilly`s Mirikizumab Helps Patients Achieve Clinical Remission and Improves Symptoms in Adults with Ulcerative Colitis in 12-Week Phase 3 Induction Study

"People living with UC often struggle to effectively manage recurring flare ups of the disease," said Lotus Mallbris, M.D., Ph.D., vice president of immunology development at Lilly. ...

ByEli Lilly and Company


Align Technology announces winner of 2020 Invisalign Ortho Summit Case Shoot-Out

Align Technology announces winner of 2020 Invisalign Ortho Summit Case Shoot-Out

His challenging Class II/Class III category treatment featured a 65 year old patient with severe mandibular crowding, flared maxillary and mandibular incisors, severe overjet, recession, and multiple missing teeth. ...

ByAlign Technology, Inc.


G-Tech Medical’s Lindsay Axelrod Presents Her Abstract

G-Tech Medical’s Lindsay Axelrod Presents Her Abstract

The study involves using non-invasive wireless electrode patches to read myoelectrical signals from the gut over 3 days in patients with Crohn’s disease. Forty patients presenting in flare, and 30 in remission will be tested at t=0,1,3 and 6 ...

ByG-Tech Medical


Dyve Biosciences wins FDA nod for Phase 2 transdermal drug delivery trial

Dyve Biosciences wins FDA nod for Phase 2 transdermal drug delivery trial

It is slated to be a double-blind, placebo-controlled, randomized clinical trial to evaluate the efficacy of DYV-700 in patients with acute gout flare. The Targets trial is set to enroll 300 subjects across 20 centers in the U.S. with the primary objective of observing DYV-700’s efficacy in reducing pain intensity and duration of pain. ...

ByDyve Biosciences


OrthoIndy Performs First Meniscus Replacements in Indiana with NUsurface Implant

OrthoIndy Performs First Meniscus Replacements in Indiana with NUsurface Implant

This injury led the 36-year-old to undergo two partial meniscectomy surgeries on his left knee, which allowed him initially to get back to playing basketball and softball. However, the knee pain flared up over the past few years to where Scott began to experience consistent knee pain during any activity, including participating in sports, playing with his kids and simply sitting ...

ByActive Implants LLC


Colibri Heart Valve Strengthens Patent Portfolio with Receipt of 12th Transcatheter Heart Valve (THV) Patent

Colibri Heart Valve Strengthens Patent Portfolio with Receipt of 12th Transcatheter Heart Valve (THV) Patent

The ‘739 Patent is a utility patent directed to an assembly that includes a transcatheter heart valve with a tubular structure away from its central portion that flares at both ends. The assembly further includes a pusher member and a delivery sheath. ...

ByColibri Heart Valve LLC


Powering the Fight Against Malaria & Aids

Powering the Fight Against Malaria & Aids

These fuels include biogas produced from the anaerobic digestion of waste, sewage gas and landfill gas. Flare gas / associated petroleum gas (APG) – Gas engines can be used to convert gas produced during the petroleum extraction process into reliable on-site power. ...

ByClarke Energy


ASTM F1192 - 11 standard guide for the measurement of single event phenomena (SEP) induced by heavy ion irradiation of semiconductor devices

ASTM F1192 - 11 standard guide for the measurement of single event phenomena (SEP) induced by heavy ion irradiation of semiconductor devices

Power transistors may be tested by the procedure called out in Method 1080 of MIL STD 750. 1.2 The procedures described here can be used to simulate and predict SEP arising from the natural space environment, including galactic cosmic rays, planetary trapped ions, and solar flares. The techniques do not, however, simulate heavy ion beam effects proposed for ...

ByASTM International


World Asthma Day: NIH research advances help people with asthma

Several current NHLBI research programs are addressing the problem of recurrent asthma flare-ups in people with otherwise good day-to-day asthma control. These programs include studying new treatment approaches for flare-ups in infants and school-age children, as well as genome-wide association studies investigating the genetic factors that make some patients ...

ByNational Institute of Environmental Health Sciences (NIEHS)

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