Gastroesophageal Articles & Analysis
19 news found
BE is found in 5–15% of all gastroesophageal reflux disease (GERD) patients. The development of BE is most often attributed to long-standing GERD, although approximately half of patients diagnosed with BE are asymptomatic. ...
The results from the myCare-004 clinical study were featured in a poster session as part of the 2022 ASCO Annual Meeting during the Gastrointestinal Cancer – Gastroesophageal Pancreatic and Hepatobiliary Track and available online as Abstract 4064. “This study confirmed that there are many dysregulated signaling pathways responsible for hallmark behaviors of cancer ...
Enrollment continues in the phase 1/2a combination study of AFM24 with the anti-PD-L1 checkpoint inhibitor atezolizumab (Tecentriq®) (AFM24-102) to treat patients with non-small cell lung cancer (EGFR wildtype), gastric and gastroesophageal junction adenocarcinoma and pancreatic/hepatocellular/biliary tract cancer. ...
PepsinCheck provides a quick, easy, comfortable solution, with saliva-based samples and a simple process. Gastroesophageal reflux disease (GERD) is a chronic and highly prevalent disorder affecting an estimated 20 percent of the US population. ...
ByRestech
The computer-assisted procedure, which is intended as an adjunct to standard four-quadrant biopsies for screening, diagnosis, or surveillance of cancerous or precancerous esophageal lesions, may be considered medically necessary for the surveillance of both Barrett’s Esophagus and chronic gastroesophageal reflux disease (GERD). “Using artificial intelligence to ...
Food and Drug Administration (FDA) granted Fast Track designation to genetically modified placental-derived NK cell therapy candidate, CYNK-101, in first line metastatic HER2/neu positive gastric and gastroesophageal junction cancers; Phase 1/2a study is ongoing FDA granted an Orphan Drug Designation to CYNK-101 for the treatment of gastric/gastroesophageal ...
Lee Moffitt Cancer Center Session Title: Gastrointestinal Cancer – Gastroesophageal, Pancreatic, and Hepatobiliary Session Date and Time: Saturday, June 4, 2022 | 8:00 a.m. ...
Unsedated TNE can be used to evaluate and diagnose a wide range of upper GI conditions that may require frequent monitoring including eosinophilic esophagitis (EoE), dysphagia, celiac disease, gastroesophageal reflux disease, Barrett’s esophagus, malabsorption, and abdominal pain. ...
ByEvoEndo
In November 2021, Celularity received clearance of its IND by the FDA for the use of CYNK-101 in combination with standard chemotherapy, trastuzumab and pembrolizumab, in patients with first-line locally advanced unresectable or metastatic HER2/neu positive gastric or gastroesophageal junction (G/GEJ) adenocarcinoma. Also in November 2021, Celularity presented preclinical data ...
CYNK-101 is an investigational genetically modified NK cell therapy designed to synergize with antibody therapeutics for difficult to treat cancers of high unmet medical need Phase 1/2a clinical trial will evaluate the safety and preliminary efficacy of CYNK-101 in combination with standard chemotherapy, trastuzumab and pembrolizumab as a first-line treatment in advanced HER2/neu positive ...
Under this agreement, GI Innovation and AstraZeneca will conduct a clinical trial assessing triplet combination regimen of GI-101, Imfinzi® (durvalumab) and chemotherapy for the treatment of small cell lung cancer, gastric/gastroesophageal junction cancer, biliary tract cancer and triple-negative breast cancer in USA, Australia and South Korea. ...
WATS3D, which is intended as an adjunct to standard four-quadrant biopsies for screening, diagnosis, or surveillance of cancerous or precancerous esophageal lesions, may be considered medically necessary for the surveillance of both Barrett’s esophagus and chronic gastroesophageal reflux disease (GERD). “Highmark Blue Cross Blue Shield’s positive medical policy ...
REDMOND, Wash – June 23, 2021 – EndoGastric Solutions® today released the GERDHelp™ mobile application that will virtually guide gastroesophageal reflux disease (GERD) sufferers through an individualized treatment pathway providing education and customized support along the patient journey. ...
Continued evolution of EndoGastric Solutions’ EsophyX technology and concomitant use of TIF 2.0 with hiatal hernia repair brings long-term GERD relief to a broader spectrum of patients REDMOND, Wash – June 17, 2020 – EndoGastric Solutions® today announced the publication of a new review article in Therapeutic Advances in Gastroenterology1 that describes the refinement of ...
(NYSE: PFE) today announced topline results of the Phase III JAVELIN Gastric 100 study evaluating avelumab as first-line maintenance therapy following induction chemotherapy in patients with unresectable, locally advanced or metastatic HER2-negative gastric or gastroesophageal junction (GEJ) cancer versus continuation of chemotherapy or best supportive care. ...
A 99-patient study confirms that a laparo-endoluminal approach reduces proton pump inhibitor medication use and significantly improves quality-of-life scores REDMOND, Wash – EndoGastric Solutions® today announced the publication of new clinical data confirming that concomitantly performed hiatal hernia (HH) repair and the Transoral Incisionless Fundoplication (TIF® 2.0) procedure ...
According to a Surgery of World Journal Gastrointest in 2016 it is estimated that up to 20 till 25 percent of Americans experience symptoms of prevalence of gastroesophageal reflux disease (GERD) weekly. ...
Being a prokinetic agent, it also has potential benefit in other indications such as proton pump inhibitor-refractory gastroesophageal reflux disease (GERD) and functional dyspepsia. Both of these conditions combined affect 50 million patients in the ...
It also has potential benefit in other indications in which a prokinetic agent could be beneficial such as gastroesophageal reflux disease (GERD). “We purchased renzapride from its original developer because we saw significant opportunity as a therapeutic to address the poorly-served therapeutic area of diabetic gastroparesis,” said Zamir S. ...