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Gene Expression Articles & Analysis
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It provides comprehensive vector construction services, including codon optimization, gene synthesis, and plasmid assembly. A variety of plasmid backbones and selection systems are available, and screening strategies can be tailored to optimize gene expression and functional activity in different host systems. Expertise in transient ...
In addition, the company offers CRISPR or siRNA technologies to help clients identify and validate targets of interest by verifying target functional pathways, proliferation, gene expression analysis and protein modification. Hit identification and optimization Creative Diagnostics provides comprehensive support for drug screening using virtual, biochemical, ...
In many research applications, such as gene expression studies, vaccine development, and gene therapy, transfection—the process of introducing nucleic acids into cells—is an essential step. ...
In metagenomics, where researchers deal with a multitude of libraries derived from diverse microbial populations, even minor errors can skew the analysis of protein functions and metabolic pathways associated with specific genes. Therefore, implementing a rigorous quality control (QC) protocol is essential to ensure the reliability of the data. ...
The incidence of landscape fires has been rising globally, leading to increased exposure to landscape fire smoke (LFS) among millions of people. The inhalation of particulate matter (PM) from LFS is associated with adverse respiratory and cardiovascular outcomes. However, the mechanisms by which LFS impacts these functions remain inadequately understood. This blog focuses on a new ...
To date, 3D cell culture systems, including scaffold-based and scaffold-free, have been widely applied in differentiation studies, drug discovery, cancer research, gene and protein expression studies, and cellular physiological studies. ...
This meticulous process allows for the precise mapping of m6A sites within RNA molecules, providing researchers with valuable insights into RNA metabolism and gene expression. MeRIP Sequencing, also known as Methylated RNA Immunoprecipitation Sequencing, offers a sophisticated approach to map and quantify m6A modifications with exceptional sensitivity and ...
ExcellGene, a renowned Swiss biologics CDMO specializing in complex protein manufacturing services, using standard CHO and HEK293 expression systems and Capricorn Scientific, a leading German manufacturer of high-quality cell culture products, have joined forces in a strategic partnership to elevate the field of biopharmaceutical ...
P53 is a potent tumor suppressor encoded by the TP53 gene on human chromosome 17. As a transcription factor, P53 coordinates the expression of target genes to promote cell cycle arrest, apoptosis, and DNA repair. In addition, P53 exerts antiproliferative effects through transcription-independent mechanisms. Mutations in the TP53 ...
Epigenetics is a field of genetics that delves into the influence of chemical modifications within the genome on gene expression and the transmission of genetic information. Of significant note are the chemical modifications 5mC (5-methylcytosine) and 5hmC (5-hydroxymethylcytosine), which play pivotal roles in the regulation of gene ...
This enzyme plays a fundamental role in various biological processes including gene expression, protein function, and metabolic activity. Thus, having a quality and reliable source of SAHH is vital for research institutions and industries to advance their understanding and application of this pivotal enzyme. ...
As several gene therapy approvals for rare disease treatment gain steam in 2023, a comprehensive set of gene therapy development solutions is released to pave richer avenues for rare disease research. ...
This technology promises to revolutionize the field of transcriptomics research, offering researchers an unprecedented window into RNA degradation patterns and elevating our comprehension of gene regulation and expression. RNA degradation is a fundamental component of gene regulation and post-transcriptional processes. ...
The simplicity and efficiency of this kit make it an ideal choice for gene expression (mRNA) analysis, copy number analysis, and SNP genotype analysis. ...
Within this collaboration, we will combine our respective technologies to try to express “bio” RNA from Dyadic’s eukaryotic C1-cells, to design, develop and commercialize messenger RNA products,” said Pascal Viguié, bYoRNA’s Chief Executive Officer. ...
Profacgen, one of the leading biotechnology companies that provides first-class protein expression services, recently announced the release of multi-protein expression service in insect cells, to help scientists conduct protein co-expression network analysis and interaction studies. ...
By sequencing full-length transcripts, researchers can uncover and study lowly expressed or rare transcripts, providing a more comprehensive understanding of the diversity of gene expression. ...
Direct sequencing provides researchers with a comprehensive and unbiased view of the transcriptome, capturing even the rarest and low-abundance transcripts previously overlooked. Novel gene isoforms, non-coding RNAs, and RNA modifications can now be unveiled, paving the way for groundbreaking discoveries across various biological processes. ...
Amerigo Scientific, a distributor focused on providing critical products and services to biomedical and life science communities, unveils 1Step RT PCR Kit for the scientific use of gene-expression analysis, transfection analysis, cDNA cloning, multiplex RT-PCR, etc. ...
Therefore, HLA typing is essential to the research of immune-related diseases, the screening of vaccine and drug target populations, the study of ethnic evolution, tissue, organ transplantations, etc. The HLA gene products can be expressed on different cell surfaces and play critical roles in antigen presentation and immune signaling. ...