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Hypoglycemia Articles & Analysis

21 news found

Analysis supporting treatment with Diamyd published in peer-reviewed scientific journal

Analysis supporting treatment with Diamyd published in peer-reviewed scientific journal

Longer time in the glycemic target range and reduced variability in blood glucose are associated with significant clinical benefits including lower risk of severe hypoglycemia and improved quality of life. About Diamyd Medical Diamyd Medical develops precision medicine therapies for type 1 diabetes. ...

ByDiamyd Medical AB


Vertex to Present New Data on VX-880 Clinical Trial at 82nd American Diabetes Association Annual Conference

Vertex to Present New Data on VX-880 Clinical Trial at 82nd American Diabetes Association Annual Conference

Abstract and publication #92-OR entitled “Persistence of Impaired Awareness of Hypoglycemia, Severe Hypoglycemic Events and Suboptimal Glycemic Control Despite Advanced Diabetes Technologies,” to be presented Saturday, June 4, 2022 at 1:45 p.m. ...

ByVertex Pharmaceuticals


Vertex Provides Updates on Phase 1/2 Clinical Trial of VX-880 for the Treatment of Type 1 Diabetes

Vertex Provides Updates on Phase 1/2 Clinical Trial of VX-880 for the Treatment of Type 1 Diabetes

VX-880 is being evaluated for patients who have T1D with impaired hypoglycemic awareness and severe hypoglycemia. VX-880 has the potential to restore the body’s ability to regulate glucose levels by restoring pancreatic islet cell function, including glucose-responsive insulin production. ...

ByVertex Pharmaceuticals


It All Starts With Patient Safety at Medovate

It All Starts With Patient Safety at Medovate

When this error occurs it can artificially raise the patient’s blood glucose sample measurement which can lead to the patient being given insulin inappropriately, potentially resulting in hypoglycemia with potential serious consequences. GLUCOSAVE® is designed to provide a visual alert to staff during the blood sampling process to prompt them to check if a glucose ...

ByMedovate


Fractyl Announces Tenth Trial Site Opened in REVITA-T2Di Study of Revita DMR for Type 2 Diabetes

Fractyl Announces Tenth Trial Site Opened in REVITA-T2Di Study of Revita DMR for Type 2 Diabetes

“The insulin-treated type 2 diabetes patient population is most at risk for complications of insulin, including hypoglycemia and excessive weight gain, but yet we as clinicians have the fewest tools to effectively treat these individuals,” said Vivian Fonseca, M.D., assistant dean for clinical research and Tullis-Tulane alumni chair in diabetes at Tulane University ...

ByFractyl Health


Zucara Therapeutics Doses First Patients in Phase 1b Trial of ZT-01

Zucara Therapeutics Doses First Patients in Phase 1b Trial of ZT-01

Other study objectives include further evaluation of the safety and tolerability of ZT-01 and evaluation of symptoms and other hormones related to hypoglycemia. Topline results are expected in the first quarter of 2022. ...

ByZucara Therapeutics Inc.


Patent for Cell Selection of Beta Cells to Treat and Potentially Cure Diabetes was Granted in Japan

Patent for Cell Selection of Beta Cells to Treat and Potentially Cure Diabetes was Granted in Japan

IsletRx comprises an expanded population of clinical grade pancreatic islet-like cluster (ILCs) cells, derived from human stem cells, that have the ability to secrete insulin when blood sugar is low and glucagon, a hormone secreted to prevent hypoglycemia, when blood sugar levels drop in response to varying sugar levels (glucose) in the blood. ...

ByKadimastem Ltd.


Zucara Therapeutics Successfully Completes Single and Multiple Ascending Dose Phase 1 Trial of ZT-01

Zucara Therapeutics Successfully Completes Single and Multiple Ascending Dose Phase 1 Trial of ZT-01

A novel treatment to prevent hypoglycemia would be a welcome tool and indispensable safeguard for people living with ...

ByZucara Therapeutics Inc.


Fractyl Announces First Patient Enrolled in Pivotal Study of Novel Procedural Therapy Revita® DMR for Type 2 Diabetes

Fractyl Announces First Patient Enrolled in Pivotal Study of Novel Procedural Therapy Revita® DMR for Type 2 Diabetes

“In collaboration with clinical sites in the United States and Europe, we look forward to evaluating Revita DMR in a segment of the type 2 diabetes population who are most at risk for hypoglycemia, weight gain and other significant complications of insulin ...

ByFractyl Health


Fractyl Announces Publication of Clinical Results from INSPIRE Study Showing Durable Insulin-Free Glycemic Control in Majority of Patients Treated

Fractyl Announces Publication of Clinical Results from INSPIRE Study Showing Durable Insulin-Free Glycemic Control in Majority of Patients Treated

This does not slow disease progression, and it brings side effects including hypoglycemia, weight gain, and other risks. Revita DMR may present an alternative that can help achieve glucose control while reducing or eliminating the need for insulin. ...

ByFractyl Health


Zucara Therapeutics Expands ZT-01 Development Program to Type 2 Diabetes

Zucara Therapeutics Expands ZT-01 Development Program to Type 2 Diabetes

(“Zucara” or the “Company”), a diabetes life sciences company developing the first once-daily therapeutic to prevent insulin-induced hypoglycemia (low blood glucose levels), today announced that it has expanded the development of ZT-01, a somatostatin receptor 2 antagonist (“SSTR2a”), to Type 2 Diabetes (“T2D”). ...

ByZucara Therapeutics Inc.


Zucara Therapeutics Expands ZT-01 Development Program to Type 2 Diabetes

Zucara Therapeutics Expands ZT-01 Development Program to Type 2 Diabetes

(“Zucara” or the “Company”), a diabetes life sciences company developing the first once-daily therapeutic to prevent insulin-induced hypoglycemia (low blood glucose levels), today announced that it has expanded the development of ZT-01, a somatostatin receptor 2 antagonist (“SSTR2a”), to Type 2 Diabetes (“T2D”). ...

ByZucara Therapeutics Inc.


Zucara Therapeutics Doses First Subject in Phase 1 Trial of ZT-01

Zucara Therapeutics Doses First Subject in Phase 1 Trial of ZT-01

The study results will help define ZT-01’s safety profile and establish doses to be used in an additional planned Phase 1 study to show the effect on glucagon during hypoglycemia in T1D patients. Insulin-induced hypoglycemia is a frequent, unintended consequence of insulin therapy for people with T1D and other types of insulin-dependent diabetes. ...

ByZucara Therapeutics Inc.


Zucara Therapeutics Doses First Subject in Phase 1 Trial of ZT-01

Zucara Therapeutics Doses First Subject in Phase 1 Trial of ZT-01

The study results will help define ZT-01’s safety profile and establish doses to be used in an additional planned Phase 1 study to show the effect on glucagon during hypoglycemia in T1D patients. Insulin-induced hypoglycemia is a frequent, unintended consequence of insulin therapy for people with T1D and other types of insulin-dependent diabetes. ...

ByZucara Therapeutics Inc.


Zucara Therapeutics Presents New Data at European Association for the Study of Diabetes

Zucara Therapeutics Presents New Data at European Association for the Study of Diabetes

Hypoglycemia is a well-documented problem for people with diabetes taking insulin. Continuous glucose monitor (CGM) technologies are increasingly used by insulin users, and are believed to be of great support to patients in reacting to impending hypoglycemia by alerting the patient to falling glucose levels. Despite this benefit, CGM users have mixed feelings ...

ByZucara Therapeutics Inc.


Zucara Therapeutics Announces US$21 Million Series A Financing

Zucara Therapeutics Announces US$21 Million Series A Financing

Hypoglycemia is associated with significant morbidity and mortality, yet there are currently no available therapeutics to prevent the condition. ZT-01 has the potential to restore the body’s ability to recover from hypoglycemia, which could improve disease management and prevent dangerous hypoglycemic episodes, potentially reducing long-term complications. ...

ByZucara Therapeutics Inc.


Zucara Therapeutics Announces US$21 Million Series A Financing

Zucara Therapeutics Announces US$21 Million Series A Financing

Hypoglycemia is associated with significant morbidity and mortality, yet there are currently no available therapeutics to prevent the condition. ZT-01 has the potential to restore the body’s ability to recover from hypoglycemia, which could improve disease management and prevent dangerous hypoglycemic episodes, potentially reducing long-term complications. ...

ByZucara Therapeutics Inc.


Woolsey Pharmaceuticals’ Financing is Oversubscribed; Two Board Members Named

Woolsey Pharmaceuticals’ Financing is Oversubscribed; Two Board Members Named

At Locemia, he led the creation and development of Baqsimi®, a needle-free repurposed rescue treatment for severe hypoglycemia; the product was acquired by Eli Lilly in 2015. Prior to Locemia, Dr. ...

ByWoolsey Pharmaceuticals, Inc.


Zucara Therapeutics Secures Grant from GlycoNet to Expand and Validate their Drug Therapy Model for Type 1 Diabetes to Type 2 Diabetes

Zucara Therapeutics Secures Grant from GlycoNet to Expand and Validate their Drug Therapy Model for Type 1 Diabetes to Type 2 Diabetes

Zucara Therapeutics Inc., a life sciences company developing the first once-daily therapeutic to prevent hypoglycemia in people with type 1 diabetes and other types of insulin-dependent diabetes, has secured a grant of $69,000 from Canadian Glycomics Network (GlycoNet) to expand and validate the model for its lead drug candidate “ZT-01” from type 1 diabetes (T1D) to ...

ByZucara Therapeutics Inc.


Aktivax wins $15 million contract with BARDA

Aktivax wins $15 million contract with BARDA

” In the near future, Aktivax will leverage the progress made under the BARDA contract to pursue consumer market emergency products such as severe allergy treatment, hypoglycemia, and opioid overdose. “Not surprisingly, the Government's need for robust, user-friendly auto-injectors with improved drug stability is similar to the needs of consumer markets” said ...

ByAktiv Pharma Group, Inc

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