In Vivo Microenvironment Articles & Analysis
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Although cancer originates from mutations accumulating within cancer cells, disease progression and treatment response are both strongly regulated by non-mutated cells within the tumour microenvironment. Significant advances have been made in recent years in the study of cancer-associated fibroblasts (CAFs). ...
Single IV cycle of PsiOxus’ T-SIGn vector enabled an otherwise non-effective dose of CAR-T cell therapy to clear primary and metastatic tumors in vivo Reprogramming of the tumor microenvironment using T-SIGn vectors could enable a variety of CAR-T therapies to overcome limitations in solid tumors Data is currently being presented at the AACR Virtual ...