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In Vivo Tests Articles & Analysis

10 news found

Understanding Lung Biomechanics In Asthma By Combining ex vivo with in vivo

Understanding Lung Biomechanics In Asthma By Combining ex vivo with in vivo

Asthma remains a complex and multifactorial disease, with airway hyperresponsiveness to methacholine being a hallmark feature. A recent study by Rojas-Ruiz et al (2025) utilizes SCIREQ’s innovative physioLens (ex vivo) and flexiVent (in vivo) platforms to shed light on the interplay between lung tissue compliance and methacholine response, offering new insights into the mechanisms ...

BySCIREQ - an emka TECHNOLOGIES Company


Alfa Chemistry Leads the Way in Tailored Preclinical Drug Research Solutions

Alfa Chemistry Leads the Way in Tailored Preclinical Drug Research Solutions

Alfa Chemistry is able to design and conduct in vivo and in vitro pharmacokinetic (PK) tests for different projects, providing complete pharmacokinetic evaluation and optimization services, including: biological target validation, early physical and chemical properties screening, metabolite identification (metid), in vitro studies, in vivo ...

ByAlfa Chemistry


Full-Scale PROTAC In Vivo Evaluation Services to Facilitate PROTAC Drug R&D

Full-Scale PROTAC In Vivo Evaluation Services to Facilitate PROTAC Drug R&D

BOC Sciences has established an advanced and comprehensive PROTAC service platform to deliver R&D outsourcing services for customers with requirements in preclinical safety evaluations, with repeatable data and a rapid research cycle. Its PROTAC in vivo evaluation services encompass general studies of toxicology and in vivo pharmacokinetics, ...

ByBOC Sciences


ASC Therapeutics, UMass Chan Medical School, and the Clinic for Special Children Announce Podium Presentation of Safety and Efficacy in Murine and Bovine Models for Novel Gene Therapy in Maple Syrup Urine Disease

ASC Therapeutics, UMass Chan Medical School, and the Clinic for Special Children Announce Podium Presentation of Safety and Efficacy in Murine and Bovine Models for Novel Gene Therapy in Maple Syrup Urine Disease

Three animal models were generated to test safety and efficacy: two murine models representing two common genetic forms of MSUD and a newborn calf naturally homozygous for a mutation that causes MSUD. ...

ByASC Therapeutics


STEMart Launches Pyrogenicity Testing Service for Medical Devices

STEMart Launches Pyrogenicity Testing Service for Medical Devices

Biocompatibility systemic toxicity tests are in vivo systemic tests used to assess systemic damage or activation of a system, not damage to individual cells or organs. Systemic toxicity tests include acute systemic toxicity tests and pyrogenic tests. “Tests for systemic ...

BySTEMart


Publication of EXALT-1 Trial in Cancer Discovery Demonstrates First AI-Supported Functional Precision Medicine Platform to Improve Cancer Treatment Outcomes

Publication of EXALT-1 Trial in Cancer Discovery Demonstrates First AI-Supported Functional Precision Medicine Platform to Improve Cancer Treatment Outcomes

The study, titled “Functional Precision Medicine Provides Clinical Benefit in Advanced Aggressive Haematological Cancers and Identifies Exceptional Responders,” illustrates the potential real-world impact of using Exscientia’s AI-supported precision medicine platform (referred to in the study as single-cell functional precision medicine or scFPM) to propose which therapy would ...

ByExscientia


Invizius announces £5.3m Series A

Invizius announces £5.3m Series A

Invizius has developed the protein manufacturing process with high confidence in purity and yield targets, and has received promising preliminary results from ex-vivo testing in human blood at University Medical Centre Groningen a leading European renal research centre. ...

ByInvizius Limited


Spotlight from Canada Economic Development on Puzzle Medical`s journey

Spotlight from Canada Economic Development on Puzzle Medical`s journey

The team then proceeded with pre-clinical in vivo out-patient testing. The results were significant. Using this pump greatly reduced blood traumas and post-operative complications. ...

ByPuzzle Medical Devices Inc.


Injectsense Receives Breakthrough Device Program Designation from FDA, Highlights Eye Sensor Performance and Path to Human Studies

Injectsense Receives Breakthrough Device Program Designation from FDA, Highlights Eye Sensor Performance and Path to Human Studies

The company conducted successful in-vivo functionality testing in animals in 2019, sending IOP data from eyes to a cloud database. ...

ByInjectsense, Inc.


ALung Announces Commercial Development of its Breakthrough Next Generation Artificial Lung

ALung Announces Commercial Development of its Breakthrough Next Generation Artificial Lung

Jeremy Kimmel, PhD, Vice President of New Technology at ALung Technologies stated, “Professor Federspiel and colleagues at the University of Pittsburgh have rapidly advanced this technology toward commercial readiness through state of the art computational, in vitro and in vivo testing, including successful 7-day and 30-day large animal studies. ...

ByLivaNova PLC

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