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In Vivo Using Articles & Analysis

19 news found

CD Bioparticles Introduces Endotoxin Free Silver Nanoparticles for Advanced Biomedical Research

CD Bioparticles Introduces Endotoxin Free Silver Nanoparticles for Advanced Biomedical Research

Silver nanoparticles (AgNPs) are increasingly being used in various fields due to their unique physical and chemical properties, including optical, electrical and thermal properties, high electrical conductivity and biological properties. These applications span the medical, food, healthcare, consumer and industrial sectors, with AgNPs being used as antibacterial ...

ByCD Bioparticles


CD Bioparticles Launches mRNA Transfection Reagents for Research Applications

CD Bioparticles Launches mRNA Transfection Reagents for Research Applications

Additionally, mRNA synthesized in vitro is inefficient for in vivo use, as it is not a stable macromolecule and is sensitive to shear stress. Furthermore, the short mRNA half-life of in vivo tends to limit sufficient protein expression. With customized delivery strategies, precise design and transformation of drugs/drug-loaded cargos, and ...

ByCD Bioparticles


Creative Diagnostics Introduces Microneutralization Assay Service for Virus Detection

Creative Diagnostics Introduces Microneutralization Assay Service for Virus Detection

Creative Diagnostics' new Microneutralization Test provides researchers with high-quality results in two days using the ELISA microtiter plates, covering target virus and infected cell culture and microneutralization assay. ...

ByCreative Diagnostics


CD Formulation Provides Pharmaceutical Testing on Tablet Fragility, Dissolution, and Disintegration

CD Formulation Provides Pharmaceutical Testing on Tablet Fragility, Dissolution, and Disintegration

The results will provide critical safety data on the bioavailability of drugs in vivo without the use of in vivo methods. At CD Formulation, a series of methods such as the test-tube method, sieve method with shaker, sieve method, and pharmacopoeial method are used to test disintegration for drugs. ...

ByCD Formulation


Novel Modulators of LDL Metabolism

Novel Modulators of LDL Metabolism

DESCRIPTION provided by applicant Heart disease is the leading cause of death for both men and women in the US accounting for nearly of all annual deaths A high cholesterol level is well known risk factors for heart disease Although blood cholesterol can be lowered using a number of marketed drugs of which statins are the leading drugs only of patients taking ...

ByShifa Biomedical Corporation


InMed Pharmaceuticals Advances Neurodegenerative Disease Program with Natural Sciences and Engineering Research Council of Canada (`NSERC`) Alliance Grant Funding

InMed Pharmaceuticals Advances Neurodegenerative Disease Program with Natural Sciences and Engineering Research Council of Canada (`NSERC`) Alliance Grant Funding

Targeting neurodegenerative diseases such as Alzheimer’s, Huntington’s and Parkinson’s Identified two lead cannabinoid analog compounds for in vivo studies NSERC grant funding supports InMed’s collaborative research projects with Dr. ...

ByInMed Pharmaceuticals Inc.


Disintegration Test Is Now Available at CD Formulation for Drug Analysis and Development

Disintegration Test Is Now Available at CD Formulation for Drug Analysis and Development

Usually, drugs in the form of tablets, capsules, and enteric-coated tablets are required to conduct disintegration testing so as to obtain critical safety data on the in vivo bioavailability of drugs without the use of in vivo methods. At CD Formulation, solution, reagents, and techniques used for disintegration testing are in ...

ByCD Formulation


STEMart Launches Pyrogenicity Testing Service for Medical Devices

STEMart Launches Pyrogenicity Testing Service for Medical Devices

Biocompatibility refers to the appropriate biological requirements for biological materials used in medical devices. Biocompatibility is also described as the ability of a device material to perform with an appropriate host response in a particular application. ...

BySTEMart


Second grant win to research Peritoneal Dialysis indication

Second grant win to research Peritoneal Dialysis indication

Haemodialysis and Peritoneal Dialysis are the two main treatment methods used today. Both have limitations due to the body’s immune reaction to the procedure. ...

ByInvizius Limited


Lineage Announces a Fifth Cell Therapy Program: Allogeneic Photoreceptor Transplants for the Treatment of Diseases Which May Lead to Blindness

Lineage Announces a Fifth Cell Therapy Program: Allogeneic Photoreceptor Transplants for the Treatment of Diseases Which May Lead to Blindness

Similar to the company’s recently announced pipeline expansion into auditory neurons for the treatment of hearing loss, Lineage has filed for intellectual property protection covering the composition and methods for generating PNCs. Based on recent in vivo data generated using the company’s PNCs, these cells may be capable of forming reconstructed ...

ByLineage Cell Therapeutics, Inc.


Mammoth Biosciences Announces Key Leadership Appointments

Mammoth Biosciences Announces Key Leadership Appointments

At Mammoth, he will lead the discovery and development of next-generation in vivo gene-editing therapeutics using Mammoth’s ultracompact CRISPR systems. ...

ByMammoth Biosciences, Inc.


Sangamo Therapeutics to Present Data From Its Next-Generation Technologies at 2022 Annual Meeting of the American Society of Gene & Cell Therapy (ASGCT)

Sangamo Therapeutics to Present Data From Its Next-Generation Technologies at 2022 Annual Meeting of the American Society of Gene & Cell Therapy (ASGCT)

TU-65) Durable, Multiplexed, Cell Engineering Using Zinc-Finger Guided Transcriptional Regulators Delivered via a Single Viral Particle Abstract No. 339 Poster Presentation – May 16; 5:30-6:30 pm ET (Board No. ...

BySangamo Therapeutics


Adaptimmune Reports Positive Results from its Pivotal SPEARHEAD-1 Trial in Patients with Synovial Sarcoma and MRCLS at CTOS

Adaptimmune Reports Positive Results from its Pivotal SPEARHEAD-1 Trial in Patients with Synovial Sarcoma and MRCLS at CTOS

SPEARHEAD-1 trial will meet its primary endpoint and data will be used to support BLA filing for afami-cel next year The overall response rate (ORR) per Independent Review was 34% (36% in patients with synovial sarcoma and 25% for patients with MRCLS) and the disease control rate was 85% As of the data cut-off, afami-cel has shown a favorable benefit:risk profile ...

ByAdaptimmune LLC


Vertex and Mammoth Biosciences Announce Collaboration to Develop In Vivo Gene-Editing Therapies for Serious Diseases

Vertex and Mammoth Biosciences Announce Collaboration to Develop In Vivo Gene-Editing Therapies for Serious Diseases

Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) and Mammoth Biosciences, a biotech company building the next generation of CRISPR products to cure and detect disease, today announced a new partnership to develop in vivo gene-editing therapies for two genetic diseases using Mammoth’s next-generation CRISPR systems. ...

ByMammoth Biosciences, Inc.


Webinar Series

Webinar Series

Find out how to use Inovotion’s cutting-edge in vivo technology in your future projects, presented by our ...

ByInovotion Sas


PsiOxus and bluebird bio Present Novel Data Combining PsiOxus T-SIGn Platform with CAR-T Therapy to Clear Primary Tumors and Metastases

PsiOxus and bluebird bio Present Novel Data Combining PsiOxus T-SIGn Platform with CAR-T Therapy to Clear Primary Tumors and Metastases

Single IV cycle of PsiOxus’ T-SIGn vector enabled an otherwise non-effective dose of CAR-T cell therapy to clear primary and metastatic tumors in vivo Reprogramming of the tumor microenvironment using T-SIGn vectors could enable a variety of CAR-T therapies to overcome limitations in solid tumors Data is currently being presented at the AACR Virtual ...

ByPsiOxus Therapeutics Ltd.


Alloy Therapeutics becomes BaseLaunch’s first dedicated antibody discovery Domain Partner

Alloy Therapeutics becomes BaseLaunch’s first dedicated antibody discovery Domain Partner

Alloy Therapeutics, founded in 2018 to empower scientists in the relentless pursuit of making better medicines for all, will provide BaseLaunch portfolio companies access to Alloy’s broad suite of antibody discovery platforms and services, including the ATX-Gx™ mouse platform, a suite of transgenic mice designed for best-in-class in vivo discovery of fully human ...

ByAlloy Therapeutics, Inc.


Endomedix, Inc. Announces Submission of Patent Application for Advanced Hemostat Technology

Endomedix, Inc. Announces Submission of Patent Application for Advanced Hemostat Technology

This novel technology can be designed to modify product performance and features to address different indications for use. For example, hemostats can be designed for use in both open and MIS procedures. ...

ByEndomedix, Inc.


Landmark Lipid-Rich Plaque (LRP) Study Results Demonstrate the Ability to Accurately Identify Patients and Plaques at Risk for Major Coronary Events

Landmark Lipid-Rich Plaque (LRP) Study Results Demonstrate the Ability to Accurately Identify Patients and Plaques at Risk for Major Coronary Events

Numerous autopsy studies have found that lipid core plaque (LCP) is the underlying cause of most coronary deaths, and ruptured lipid cores are thought to cause most MACE events in vivo. Intravascular NIRS was developed, validated, and labeled for the detection of LCP, and preliminary small-scale clinical trials have demonstrated the clinical feasibility of NIRS detection of ...

ByInfraredx, Inc.

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