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Inflammatory Activation Articles & Analysis

9 news found

Dual Benefits of Compound 17B For Pulmonary Arterial Hypertension

Dual Benefits of Compound 17B For Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a progressive, life-threatening condition characterized by increased pulmonary arterial pressure, vascular remodeling, and persistent inflammation. Despite advances in treatment, current therapies—such as sildenafil, iloprost, and riociguat—primarily focus on reducing symptoms by dilating blood vessels. Unfortunately, these therapies do ...

BySCIREQ - an emka TECHNOLOGIES Company


Immune-Onc Therapeutics Receives China Investigational New Drug (IND) Approval for the Phase 1 Study of IO-108, a Novel Antagonist Antibody Targeting LILRB2 (ILT4), in Patients with Solid Tumors

Immune-Onc Therapeutics Receives China Investigational New Drug (IND) Approval for the Phase 1 Study of IO-108, a Novel Antagonist Antibody Targeting LILRB2 (ILT4), in Patients with Solid Tumors

Ex vivo studies show that treatment with IO-108 produces pro-inflammatory activity and an enhanced antigen-presenting cell (APC) phenotype to multiple stimuli, including T cell activators, and STING and TLR agonists. As a single agent, IO-108 reverts the anti-inflammatory myeloid cell phenotype caused by “tumor ...

ByImmune-Onc Therapeutics, Inc.


Start Lab 2021: Life Science winners announced

Start Lab 2021: Life Science winners announced

The first prize in this category was won by PerFormS, a start-up from Modena which has developed the first alternative drug to cortisone for the long-term treatment of psoriasis, enhancing the anti-inflammatory activity of an endogenous molecule with no side effects. ...

ByAngiodroid Spa


SetPoint Medical CEO Murthy Simhambhatla Named to AIMBE College of Fellows

SetPoint Medical CEO Murthy Simhambhatla Named to AIMBE College of Fellows

SetPoint Medical’s bioelectronic medicine platform is intended to offer patients and providers a treatment alternative for rheumatoid arthritis, inflammatory bowel disease and other chronic autoimmune conditions with potentially less risk and cost than drug therapy. The company is developing a novel bioelectronic medicine platform that stimulates the vagus nerve to ...

BySetpoint Medical Corporation


SetPoint Medical Receives FDA Breakthrough Device Designation for its Novel Bioelectronic Platform

SetPoint Medical Receives FDA Breakthrough Device Designation for its Novel Bioelectronic Platform

SetPoint’s investigational bioelectronic medicine platform stimulates the vagus nerve to activate the endogenous inflammatory reflex and thereby reduce inflammation. ...

BySetpoint Medical Corporation


SetPoint Medical Receives IDE Approval for U.S. Pivotal Trial to Study its Bioelectronic Platform in Rheumatoid Arthritis Patients

SetPoint Medical Receives IDE Approval for U.S. Pivotal Trial to Study its Bioelectronic Platform in Rheumatoid Arthritis Patients

SetPoint Medical’s bioelectronic medicine platform is intended to offer patients and providers a treatment alternative for rheumatoid arthritis, inflammatory bowel disease and other chronic autoimmune conditions with potentially less risk and cost than drug therapy. The company is developing a novel bioelectronic medicine platform that stimulates the vagus nerve to ...

BySetpoint Medical Corporation


SetPoint Medical to Present at Canaccord Genuity Medical Technologies & Diagnostics Forum 2019

SetPoint Medical to Present at Canaccord Genuity Medical Technologies & Diagnostics Forum 2019

SetPoint Medical’s bioelectronic medicine platform is intended to offer patients and providers a treatment alternative for rheumatoid arthritis, inflammatory bowel disease and other chronic autoimmune conditions with potentially less risk and cost than drug therapy. The company is developing a novel bioelectronic medicine platform that stimulates the vagus nerve to ...

BySetpoint Medical Corporation


SetPoint Medical to Present at Canaccord Genuity Medical Technologies & Diagnostics Forum 2019

SetPoint Medical to Present at Canaccord Genuity Medical Technologies & Diagnostics Forum 2019

SetPoint Medical’s bioelectronic medicine platform is intended to offer patients and providers a treatment alternative for rheumatoid arthritis, inflammatory bowel disease and other chronic autoimmune conditions with potentially less risk and cost than drug therapy. The company is developing a novel bioelectronic medicine platform that stimulates the vagus nerve to ...

BySetpoint Medical Corporation


Setpoint Medical announces oral presentation of results from U.S. Pilot Study in Rheumatoid Arthritis Patients at American College of Rheumatology (ACR) Annual Meeting 2019

Setpoint Medical announces oral presentation of results from U.S. Pilot Study in Rheumatoid Arthritis Patients at American College of Rheumatology (ACR) Annual Meeting 2019

SetPoint Medical’s bioelectronic medicine platform is intended to offer patients and providers a treatment alternative for rheumatoid arthritis, inflammatory bowel disease and other chronic autoimmune conditions with potentially less risk and cost than drug therapy. The company is developing a novel bioelectronic medicine platform that stimulates the vagus nerve to ...

BySetpoint Medical Corporation

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