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Limb Amputation Articles & Analysis

26 news found

Reva medical announces closing of strategic financing

Reva medical announces closing of strategic financing

We believe the REVA absorbable scaffold has the potential to reduce limb amputations, and possibly save lives.” In addition to the MOTIV scaffold, REVA is in the final development stages for their TyroSphere embolic bead platform. ...

ByReva Medical LLC


£1.1 million project to develop new biodegradable stents

£1.1 million project to develop new biodegradable stents

Severe peripheral vascular disease (PVD) is caused by the formation of blockages in arteries, which reduces blood supply to the brain, heart, kidneys and limbs causing strokes, heart attacks, kidney failure and limb amputations. ...

ByArterius Limited


Rivaroxaban (Xarelto) approved in Japan for patients with peripheral artery disease (PAD) after revascularisation

Rivaroxaban (Xarelto) approved in Japan for patients with peripheral artery disease (PAD) after revascularisation

It´s the first trial to demonstrate the benefits of dual pathway inhibition - with the anticoagulant Xarelto in combination with the antiplatelet aspirin - in these PAD patients at high risk of major adverse cardiovascular events (MACE) and especially major adverse limb events (MALE). "This approval is an important advance for patients with PAD in Japan," said Dr. ...

ByBayer AG


CARDIONOVUM announces the first Signature RCT patient enrollment

CARDIONOVUM announces the first Signature RCT patient enrollment

Safety: Freedom from device- and procedure-related death through 30 days and a composite of major target limb amputation and CD-TVR @ 12 months. Miquel Craven-Bartle Capella CEO of Cardionovum® commented: “We are very happy with this first enrollment. ...

ByCARDIONOVUM GmbH


Neuros Medical Announces Completion of QUEST Pivotal Trial 90-day Primary Endpoints

Neuros Medical Announces Completion of QUEST Pivotal Trial 90-day Primary Endpoints

Neuros Medical, a bioelectric technology company, has developed the Altius system for the treatment of chronic post-amputation pain (Phantom Limb Pain and Residual Limb Pain). Altius incorporates the Company’s patented platform technology, On-Demand Bioelectric Nerve Block. ...

ByNeuros Medical, Inc.


Hemostemix Announces Pete Pavlin, P.Eng., Vice-President Operations

Hemostemix Announces Pete Pavlin, P.Eng., Vice-President Operations

ACP-01 has been used to treat over 300 patients, and it is the subject of a randomized, placebo-controlled, double-blind trial of its safety and efficacy in patients with advanced critical limb ischemia who have exhausted all other options to save their limb from amputation. ...

ByHemostemix Inc.


Hemostemix Announces Rick Groome as Special Advisor to the CEO

Hemostemix Announces Rick Groome as Special Advisor to the CEO

ACP-01 has been used to treat over 300 patients, and it is the subject of a randomized, placebo-controlled, double blind trial of its safety and efficacy in patients with advanced critical limb ischemia who have exhausted all other options to save their limb from amputation. ...

ByHemostemix Inc.


Hemostemix Announces Settlement Agreement

Hemostemix Announces Settlement Agreement

ACP-01 has been used to treat over 300 patients, and it is the subject of a randomized, placebo-controlled, double blind trial of its safety and efficacy in patients with advanced critical limb ischemia who have exhausted all other options to save their limb from amputation. ...

ByHemostemix Inc.


Aurealis Therapeutics Publishes First Study on Four-in-One-Combination Therapy Using Live Lactococcus Lactis Expressing Three Human Therapeutic Proteins for the Treatment of Chronic Non-Healing Wounds

Aurealis Therapeutics Publishes First Study on Four-in-One-Combination Therapy Using Live Lactococcus Lactis Expressing Three Human Therapeutic Proteins for the Treatment of Chronic Non-Healing Wounds

“Diabetic ulcers are the leading cause of non-traumatic lower limb amputations, and dramatically increase patient mortality. Despite a huge unmet need, no pharmacological wound healing product has been approved for more than 10 years,” said Thomas Wirth, CSO of Aurealis Therapeutics. ...

ByAurealis Therapeutics


Hemostemix Announces Closing of UNIT Private Placement

Hemostemix Announces Closing of UNIT Private Placement

ACP-01 has been used to treat over 300 patients, and it is the subject of a randomized, placebo-controlled, double blind trial of its safety and efficacy in patients with advanced critical limb ischemia who have exhausted all other options to save their limb from amputation. ...

ByHemostemix Inc.


Hemostemix Partners with My Next Health, Obtains USD $150,000 Subscription at CAD $0.25 Per Unit, and Incorporates Functional Genomics

Hemostemix Partners with My Next Health, Obtains USD $150,000 Subscription at CAD $0.25 Per Unit, and Incorporates Functional Genomics

ACP-01 is the subject of a randomized, placebo-controlled, double blind trial of its safety and efficacy in patients with advanced critical limb ischemia who have exhausted all other options to save their limb from amputation. ...

ByHemostemix Inc.


Research Finds All-Cause Hospitalizations are Nearly Three Times More Likely During a Diabetic Foot Ulcer Episode

Research Finds All-Cause Hospitalizations are Nearly Three Times More Likely During a Diabetic Foot Ulcer Episode

SOMERVILLE, Mass., January 18, 2022 — Podimetrics, a virtual care support company dedicated to preventing costly and deadly diabetic amputations, today announced results from its latest research, which compared the health of individuals during and after periods of diabetic foot ulceration — open sores or wounds on the foot, which commonly occur among those with ...

ByPodimetrics Inc.


Effects of prosthetic limb prescription on 3-year mortality among Veterans with lower-limb amputation

Effects of prosthetic limb prescription on 3-year mortality among Veterans with lower-limb amputation

Method: Retrospective observational study on 4,578 Veterans hospitalized for LLA and discharged 2003- 2004, looking at time to all-cause mortality from the amputation surgical date up to the 3 yr anniversary. Results: 1,300 (28.4%) persons received a prescription for a prosthetic limb within 1 yr after the surgical amputation. ...

ByiFIT Prosthetics, LLC


Hemostemix to combine ACP-01 with Dr. James Shapiro’s Islet Cells to treat Type 1 Diabetes

Hemostemix to combine ACP-01 with Dr. James Shapiro’s Islet Cells to treat Type 1 Diabetes

The combination of ACP-01, an autologous angiogenic cell precursor that has demonstrated improvement of angiogenesis in the heart and limbs of individuals who suffer from ischemia, and cell transplants from human islets or stem cells, hold huge promise in the treatment of diabetes. ...

ByHemostemix Inc.


Hemostemix Announces Soft Lock of Database as Source Document Verification Completed

Hemostemix Announces Soft Lock of Database as Source Document Verification Completed

ACP-01 has been used to treat over 300 patients, and it is the subject of a randomized, placebo-controlled, double blind trial of its safety and efficacy in patients with advanced critical limb ischemia who have exhausted all other options to save their limb from amputation. ...

ByHemostemix Inc.


Hemostemix Announces Dr. Fraser C. Henderson Sr., MD, as Chief Medical Officer

Hemostemix Announces Dr. Fraser C. Henderson Sr., MD, as Chief Medical Officer

ACP-01 has been used to treat over 300 patients, and it is the subject of a randomized, placebo-controlled, double blind trial of its safety and efficacy in patients with advanced critical limb ischemia who have exhausted all other options to save their limb from amputation. ...

ByHemostemix Inc.


Hemostemix Announces the Second Stem Cell Recipient Interview: One Week to no Chest Pain

Hemostemix Announces the Second Stem Cell Recipient Interview: One Week to no Chest Pain

ACP-01 has been used to treat over 300 patients, and it is the subject of a randomized, placebo-controlled, double blind trial of its safety and efficacy in patients with advanced critical limb ischemia who have exhausted all other options to save their limb from amputation. ...

ByHemostemix Inc.


Neuros Medical Announces Completion of Enrollment in the QUEST Pivotal Clinical Study for Chronic Post-Amputation Pain

Neuros Medical Announces Completion of Enrollment in the QUEST Pivotal Clinical Study for Chronic Post-Amputation Pain

Neuros Medical, Inc., a medical device company developing innovative high-frequency nerve block technology for patients with intractable post-amputation pain, announced today the completion of enrollment in its pivotal QUEST (High-FreQUEncy Nerve Block for PoST-Amputation Pain) study. ...

ByNeuros Medical, Inc.


Neuros Medical Receives FDA Breakthrough Device Designation for its Novel Altius High Frequency Nerve Block System

Neuros Medical Receives FDA Breakthrough Device Designation for its Novel Altius High Frequency Nerve Block System

In the United States alone, there are nearly two million lower limb amputees, with 160,000 new amputations occurring annually. Chronic post-amputation pain is a significant unmet medical need, as existing treatment options are limited, and consist primarily of opioids and gabapentinoids. Chronic post-amputation pain is ...

ByNeuros Medical, Inc.


Research Finds Nearly 40% of Diabetes Patients who Suffer a Lower Extremity Amputation Endure Another Within Five Years

Research Finds Nearly 40% of Diabetes Patients who Suffer a Lower Extremity Amputation Endure Another Within Five Years

” The researchers found that one year after a patient’s first amputation, there is a 19 percent reamputation rate in both the same limb or the opposite limb. Five years after the first amputation, the reamputation rate is 37.1 percent for all reamputations, and 20.5 percent for a reamputation of the opposite ...

ByPodimetrics Inc.

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