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Mechanical Ventilation Articles & Analysis

45 news found

Validating The BLEO-Induced Mouse Model For Drug Discovery

Validating The BLEO-Induced Mouse Model For Drug Discovery

Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by progressive scarring of the lungs, which severely impairs lung function over time. Developing effective treatments for IPF has been a challenge for the medical community, as the mechanisms driving this disease are complex and not fully understood. To accelerate drug discovery, animal models that closely mimic the ...

BySCIREQ - an emka TECHNOLOGIES Company


World TB Day and Infection Control Resources in New York City to Help Prevent New Cases

World TB Day and Infection Control Resources in New York City to Help Prevent New Cases

In addition to air testing utilizing highly sensitive real-time Polymerase Chain Reaction (PCR) techniques to help to stop the spread of Mycobacterium tuberculosis, CTSI also helps to mitigate exposure risks through their expertise in mechanical ventilation, engineering controls, and other methods to protect patients, workers, and building occupants in healthcare ...

ByCochrane & Associates, LLC


Enalare Therapeutics Receives Orphan Drug Designation From the U.S. FDA on ENA-001 for the Treatment of Apnea of Prematurity (AoP)

Enalare Therapeutics Receives Orphan Drug Designation From the U.S. FDA on ENA-001 for the Treatment of Apnea of Prematurity (AoP)

ENA-001, a New Chemical Entity (NCE) with a novel mechanism of action as an agnostic respiratory stimulant, has previously been granted Rare Pediatric Disease designation for the Treatment of AoP by the FDA, with eligibility for a priority review voucher (PRV). ...

ByEnalare Therapeutics Inc.


Enalare Therapeutics Receives an Additional Award Worth Up to $50 Million From BARDA, Expanding Its Partnership in Development of ENA-001

Enalare Therapeutics Receives an Additional Award Worth Up to $50 Million From BARDA, Expanding Its Partnership in Development of ENA-001

ENA-001, a New Chemical Entity (NCE) with a novel mechanism of action, has broad applications as an agnostic respiratory stimulant. ...

ByEnalare Therapeutics Inc.


Positive Clinical Results for Bluejay’s Symphony IL-6 Test Presented at AACC 2022

Positive Clinical Results for Bluejay’s Symphony IL-6 Test Presented at AACC 2022

” Results from the analytical and clinical studies conclude that the Symphony IL-6 Test is an innovative technology for use in Emergency Department and Intensive Care Unit settings to identify COVID-19 patients at higher risk for severe disease, including the requirement for Invasive Mechanical Ventilation (IMV). This conclusion is based on the study ...

ByBluejay Diagnostics, Inc.


N8 Medical Announces First-in-Human Use of its CeraShield™ Endotracheal Tube

N8 Medical Announces First-in-Human Use of its CeraShield™ Endotracheal Tube

N8 Medical, LLC (N8 Medical) today announced its first-in-human clinical trials of its flagship CeraShield™ endotracheal tube (CeraShield™ ETT) for intensive care unit patients expected to require mechanical ventilation for more than 48 hours. N8 Medical is encouraged by preliminary study data and believes that the CeraShield™ ETT will ...

ByN8 Medical, LLC


Enalare Therapeutics Receives a National Institutes of Health (NIH) Grant Award

Enalare Therapeutics Receives a National Institutes of Health (NIH) Grant Award

"This funding supports further development of ENA001, which we believe has the potential to improve the standard of care in treating drug-induced respiratory depression with its unique mechanism of action as an agnostic respiratory stimulant." "The drug overdose epidemic in the United States continues to escalate and is growing in complexity with an ever-greater percentage of ...

ByEnalare Therapeutics Inc.


Enalare Therapeutics Announces Positive Topline Results With ENA001 in a Propofol Induced Respiratory Depression Study

Enalare Therapeutics Announces Positive Topline Results With ENA001 in a Propofol Induced Respiratory Depression Study

Important Study Results Included: Determination of increased ventilatory response (minute ventilation) with dosing of ENA001 under hypoxic and hypercapnic conditions in conjunction with low and high doses of propofol. ...

ByEnalare Therapeutics Inc.


World TB Day and Preventing New Cases in Healthcare Facilities and Correctional Institutions in Puerto Rico

World TB Day and Preventing New Cases in Healthcare Facilities and Correctional Institutions in Puerto Rico

Zimmetry’s building science professionals can help to mitigate exposure concerns with their expertise in mechanical ventilation, engineering controls and other methods to protect building occupants in Puerto Rico and throughout the Caribbean. ...

ByCochrane & Associates, LLC


It All Starts With Patient Safety at Medovate

It All Starts With Patient Safety at Medovate

HUMIDICARE® is a novel Heat and Moisture Exchanger (HME) which visually alerts clinical staff to a dual humidification error in mechanical ventilation circuits. Artificial humidification systems are used with ventilated patients in the operating theatre or intensive care unit. ...

ByMedovate


Lungpacer Medical Accelerates Pivotal Clinical Study with AeroPace™ System

Lungpacer Medical Accelerates Pivotal Clinical Study with AeroPace™ System

Lungpacer Medical, a leading medical device innovation company, today announced the introduction of the AeroPace™ System, a next generation product, into the RESCUE 3 pivotal clinical study studying faster ventilator independence. Lungpacer is dedicated to natural breathing by developing minimally invasive technologies designed to help patients wean off ...

ByLungpacer Medical Inc.


Enalare Files Additional Patent Application for Lead Compound ENA-001 - Enhancing Potential Global Exclusivity Through 2042

Enalare Files Additional Patent Application for Lead Compound ENA-001 - Enhancing Potential Global Exclusivity Through 2042

About ENA-001 Enalare's lead compound, ENA-001, is a one-of-a-kind new chemical entity (NCE) designed as an agnostic respiratory stimulant. The compound has a unique mechanism of action that affects ventilation via the peripheral chemoreceptor pathway in the carotid bodies. The compound utilizes the body's own ventilation control system to ...

ByEnalare Therapeutics Inc.


CytoSorbents Announces Publication of U.S. CTC Multicenter Registry Results Using CytoSorb in Critically Ill COVID-19 Patients on Extracorporeal Membrane Oxygenation (ECMO)

CytoSorbents Announces Publication of U.S. CTC Multicenter Registry Results Using CytoSorb in Critically Ill COVID-19 Patients on Extracorporeal Membrane Oxygenation (ECMO)

Chan continued, “ECMO is a machine that pumps and oxygenates blood outside the body when a patient’s lungs are so diseased that mechanical ventilation fails. Without ECMO, these patients – often considered among the sickest in the ICU – would normally die. ...

ByCytoSorbents Corporation


Enalare Therapeutics Receives Rare Pediatric Disease Designation for Lead Compound ENA-001 for the Treatment of Apnea of Prematurity

Enalare Therapeutics Receives Rare Pediatric Disease Designation for Lead Compound ENA-001 for the Treatment of Apnea of Prematurity

About ENA-001 Enalare's lead compound, ENA-001, is a one-of-a-kind new chemical entity designed as an agnostic respiratory stimulant. The compound has a unique mechanism of action that affects ventilation via the peripheral chemoreceptor pathways in the carotid body. The compound utilizes the body's own ventilation control system to beneficially ...

ByEnalare Therapeutics Inc.


Enalare Therapeutics Files New Patent Application for Lead Product ENA-001 - Potentially Extending Global Exclusivity Through 2042

Enalare Therapeutics Files New Patent Application for Lead Product ENA-001 - Potentially Extending Global Exclusivity Through 2042

About ENA-001 Enalare's lead product, ENA-001, is a one-of-a-kind new chemical entity (NCE) designed as an agnostic respiratory stimulant. The product has a unique mechanism of action that affects ventilation via the peripheral chemoreceptor pathway in the carotid bodies. The product utilizes the body's own ventilation control system to ...

ByEnalare Therapeutics Inc.


FDA Grants the Hemolung® De Novo Clearance

FDA Grants the Hemolung® De Novo Clearance

“The Hemolung will be an important new treatment modality for acute respiratory failure to avoid or mitigate the harms from invasive mechanical ventilation. FDA clearance of the Hemolung is a game-changer for the treatment of these critically ill patients and will usher in a new era of extracorporeal lung support,” said Steven Conrad, MD, PhD, MCCM, ...

ByLivaNova PLC


Enalare Therapeutics Announces First Subject Dosed With Lead Product ENA-001 in a Propofol-Induced Respiratory Depression Study

Enalare Therapeutics Announces First Subject Dosed With Lead Product ENA-001 in a Propofol-Induced Respiratory Depression Study

About ENA-001 Enalare's lead product ENA-001 is a one-of-a-kind new chemical entity designed as an agnostic respiratory stimulant. The product has a unique mechanism of action that affects ventilation via the peripheral chemoreceptor pathways in the carotid body. The product utilizes the body's own ventilation control system to beneficially ...

ByEnalare Therapeutics Inc.


Avery Biomedical Devices’ Nextgen Diaphragm Pacing Transmitter, Spirit, Earns FDA Approval – Now Available

Avery Biomedical Devices’ Nextgen Diaphragm Pacing Transmitter, Spirit, Earns FDA Approval – Now Available

For patients who do meet the criteria, diaphragm pacemakers have been found to be a better alternative to mechanical ventilators. They offer greater mobility and independence; the ability to more easily perform daily activities like getting dressed, bathing and transferring from a wheelchair; lower risk of infections, pneumonia, collapsed lungs, airway injuries ...

ByAvery Biomedical Devices, Inc.


National Patient Safety Agency Alert Concerning Nebulisers

National Patient Safety Agency Alert Concerning Nebulisers

Sitting easily in line and without the need to break the circuit7, Aerogen is suitable for multiple areas across the hospital including those providing mechanical ventilation, non-invasive ventilation, high flow nasal cannula oxygen therapy as well as use in spontaneously breathing patients on wards, emergency departments and outpatients2. ...

ByAerogen


Data from Eli Lilly’s COV-BARRIER trial shows baricitinib reduced deaths in hospitalised COVID-19 patients by 38%

Data from Eli Lilly’s COV-BARRIER trial shows baricitinib reduced deaths in hospitalised COVID-19 patients by 38%

The trial did not meet statistical significance on the primary endpoint, defined as a difference in the proportion of participants progressing to the first occurrence of non-invasive ventilation including high flow oxygen or invasive mechanical ventilation including extracorporeal membrane oxygenation (ECMO) or death by Day 28. ...

ByBenevolent

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